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Extracellular Hsp90α stimulates a unique innate gene profile in microglial cells with simultaneous activation of Nrf2 and protection from oxidative stress.
Okusha Y, Lang BJ, Murshid A, Borges TJ, Holton KM, Clark-Matott J, Doshi S, Ikezu T, Calderwood SK. Okusha Y, et al. Among authors: ikezu t. Cell Stress Chaperones. 2022 Sep;27(5):461-478. doi: 10.1007/s12192-022-01279-9. Epub 2022 Jun 10. Cell Stress Chaperones. 2022. PMID: 35689138 Free PMC article.
Publisher Correction: Extracellular Hsp90α stimulates a unique innate gene profile in microglial cells with simultaneous activation of Nrf2 and protection from oxidative stress.
Okusha Y, Lang BJ, Murshid A, Borges TJ, Holton KM, Clark-Matott J, Doshi S, Ikezu T, Calderwood SK. Okusha Y, et al. Among authors: ikezu t. Cell Stress Chaperones. 2022 Sep;27(5):479-483. doi: 10.1007/s12192-022-01285-x. Cell Stress Chaperones. 2022. PMID: 35831741 Free PMC article. No abstract available.
Enrichment of Neurodegenerative Microglia Signature in Brain-Derived Extracellular Vesicles Isolated from Alzheimer's Disease Mouse Models.
Muraoka S, Jedrychowski MP, Iwahara N, Abdullah M, Onos KD, Keezer KJ, Hu J, Ikezu S, Howell GR, Gygi SP, Ikezu T. Muraoka S, et al. Among authors: ikezu s, ikezu t. J Proteome Res. 2021 Mar 5;20(3):1733-1743. doi: 10.1021/acs.jproteome.0c00934. Epub 2021 Feb 3. J Proteome Res. 2021. PMID: 33534581 Free PMC article.
Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer's disease.
Yin Z, Herron S, Silveira S, Kleemann K, Gauthier C, Mallah D, Cheng Y, Margeta MA, Pitts KM, Barry JL, Subramanian A, Shorey H, Brandao W, Durao A, Delpech JC, Madore C, Jedrychowski M, Ajay AK, Murugaiyan G, Hersh SW, Ikezu S, Ikezu T, Butovsky O. Yin Z, et al. Among authors: ikezu s, ikezu t. Nat Neurosci. 2023 Jul;26(7):1196-1207. doi: 10.1038/s41593-023-01355-y. Epub 2023 Jun 8. Nat Neurosci. 2023. PMID: 37291336
APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints.
Yin Z, Rosenzweig N, Kleemann KL, Zhang X, Brandão W, Margeta MA, Schroeder C, Sivanathan KN, Silveira S, Gauthier C, Mallah D, Pitts KM, Durao A, Herron S, Shorey H, Cheng Y, Barry JL, Krishnan RK, Wakelin S, Rhee J, Yung A, Aronchik M, Wang C, Jain N, Bao X, Gerrits E, Brouwer N, Deik A, Tenen DG, Ikezu T, Santander NG, McKinsey GL, Baufeld C, Sheppard D, Krasemann S, Nowarski R, Eggen BJL, Clish C, Tanzi RE, Madore C, Arnold TD, Holtzman DM, Butovsky O. Yin Z, et al. Among authors: ikezu t. Nat Immunol. 2023 Nov;24(11):1839-1853. doi: 10.1038/s41590-023-01627-6. Epub 2023 Sep 25. Nat Immunol. 2023. PMID: 37749326
139 results