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Year Number of Results
2002 3
2003 3
2005 1
2006 4
2007 3
2008 1
2009 2
2010 1
2011 5
2012 6
2013 4
2014 9
2015 5
2016 5
2017 4
2018 3
2019 8
2020 9
2021 10
2022 11
2023 6
2024 2

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96 results

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Page 1
Longitudinal alterations in brain perfusion and vascular reactivity in the zQ175DN mouse model of Huntington's disease.
Vasilkovska T, Salajeghe S, Vanreusel V, Van Audekerke J, Verschuuren M, Hirschler L, Warnking J, Pintelon I, Pustina D, Cachope R, Mrzljak L, Muñoz-Sanjuan I, Barbier EL, De Vos WH, Van der Linden A, Verhoye M. Vasilkovska T, et al. Among authors: munoz sanjuan i. J Biomed Sci. 2024 Apr 16;31(1):37. doi: 10.1186/s12929-024-01028-3. J Biomed Sci. 2024. PMID: 38627751 Free PMC article.
Diffusion MRI marks progressive alterations in fiber integrity in the zQ175DN mouse model of Huntington's disease.
Vidas-Guscic N, van Rijswijk J, Van Audekerke J, Jeurissen B, Nnah I, Tang H, Muñoz-Sanjuan I, Pustina D, Cachope R, Van der Linden A, Bertoglio D, Verhoye M. Vidas-Guscic N, et al. Among authors: munoz sanjuan i. Neurobiol Dis. 2024 Apr;193:106438. doi: 10.1016/j.nbd.2024.106438. Epub 2024 Feb 15. Neurobiol Dis. 2024. PMID: 38365045 Free article.
Identification and Optimization of RNA-Splicing Modulators as Huntingtin Protein-Lowering Agents for the Treatment of Huntington's Disease.
Liu L, Malagu K, Haughan AF, Khetarpal V, Stott AJ, Esmieu W, Vater HD, Webster SJ, Van de Poël AJ, Clissold C, Cosgrove B, Sutton B, Spencer JA, Breccia P, Gancia E, Bonomo S, Ladduwahetty T, Lazari O, Patel H, Atton HC, Clifton S, Mota DM, Magnani D, O'Neill A, Stebbeds M, Macabuag N, Todd D, Herva ME, Mitchell P, Visser M, Compte Sancerni S, Grand Moursel L, da Silva M, Kritikou E, Heikkinen TT, Bolkvadze T, Fodale V, Spadafora D, Daldin M, Bresciani A, Mangette JE, Doherty EM, Lee MR, Herbst T, Monteagudo E, Macdonald D, Plotnikov NV, Chambers M, McAllister G, Muňoz-Sanjuan I, Dominguez C. Liu L, et al. Among authors: munoz sanjuan i. J Med Chem. 2023 Sep 28;66(18):13205-13246. doi: 10.1021/acs.jmedchem.3c01173. Epub 2023 Sep 15. J Med Chem. 2023. PMID: 37712656
In Vivo Cerebral Imaging of Mutant Huntingtin Aggregates Using 11C-CHDI-180R PET in a Nonhuman Primate Model of Huntington Disease.
Bertoglio D, Weiss AR, Liguore W, Martin LD, Hobbs T, Templon J, Srinivasan S, Dominguez C, Munoz-Sanjuan I, Khetarpal V, Verhaeghe J, Staelens S, Link J, Liu L, Bard JA, McBride JL. Bertoglio D, et al. Among authors: munoz sanjuan i. J Nucl Med. 2023 Oct;64(10):1581-1587. doi: 10.2967/jnumed.123.265569. Epub 2023 Aug 17. J Nucl Med. 2023. PMID: 37591545 Free PMC article.
Resting-state fMRI reveals longitudinal alterations in brain network connectivity in the zQ175DN mouse model of Huntington's disease.
Vasilkovska T, Adhikari MH, Van Audekerke J, Salajeghe S, Pustina D, Cachope R, Tang H, Liu L, Muñoz-Sanjuán I, Van der Linden A, Verhoye M. Vasilkovska T, et al. Among authors: munoz sanjuan i. Neurobiol Dis. 2023 Jun 1;181:106095. doi: 10.1016/j.nbd.2023.106095. Epub 2023 Mar 22. Neurobiol Dis. 2023. PMID: 36963694 Free article.
Subtyping monogenic disorders: Huntington disease.
Sturchio A, Duker AP, Muñoz-Sanjuan I, Espay AJ. Sturchio A, et al. Among authors: munoz sanjuan i. Handb Clin Neurol. 2023;193:171-184. doi: 10.1016/B978-0-323-85555-6.00003-5. Handb Clin Neurol. 2023. PMID: 36803810 Review.
Design and Evaluation of [18F]CHDI-650 as a Positron Emission Tomography Ligand to Image Mutant Huntingtin Aggregates.
Liu L, Johnson PD, Prime ME, Khetarpal V, Brown CJ, Anzillotti L, Bertoglio D, Chen X, Coe S, Davis R, Dickie AP, Esposito S, Gadouleau E, Giles PR, Greenaway C, Haber J, Halldin C, Haller S, Hayes S, Herbst T, Herrmann F, Heßmann M, Hsai MM, Khani Y, Kotey A, Lembo A, Mangette JE, Marriner GA, Marston RW, Mills MR, Monteagudo E, Forsberg-Morén A, Nag S, Orsatti L, Sandiego C, Schaertl S, Sproston J, Staelens S, Tookey J, Turner PA, Vecchi A, Veneziano M, Muñoz-Sanjuan I, Bard J, Dominguez C. Liu L, et al. Among authors: munoz sanjuan i. J Med Chem. 2023 Jan 12;66(1):641-656. doi: 10.1021/acs.jmedchem.2c01585. Epub 2022 Dec 22. J Med Chem. 2023. PMID: 36548390
Benefits of global mutant huntingtin lowering diminish over time in a Huntington's disease mouse model.
Marchionini DM, Liu JP, Ambesi-Impiombato A, Kerker K, Cirillo K, Bansal M, Mushlin R, Brunner D, Ramboz S, Kwan M, Kuhlbrodt K, Tillack K, Peters F, Rauhala L, Obenauer J, Greene JR, Hartl C, Khetarpal V, Lager B, Rosinski J, Aaronson J, Alam M, Signer E, Muñoz-Sanjuán I, Howland D, Zeitlin SO. Marchionini DM, et al. Among authors: munoz sanjuan i. JCI Insight. 2022 Oct 24;7(20):e161769. doi: 10.1172/jci.insight.161769. JCI Insight. 2022. PMID: 36278490 Free PMC article.
Biodistribution and dosimetry in human healthy volunteers of the PET radioligands [11C]CHDI-00485180-R and [11C]CHDI-00485626, designed for quantification of cerebral aggregated mutant huntingtin.
Delva A, Koole M, Serdons K, Bormans G, Liu L, Bard J, Khetarpal V, Dominguez C, Munoz-Sanjuan I, Wood A, Skinbjerg M, Wang Y, Vandenberghe W, Van Laere K. Delva A, et al. Among authors: munoz sanjuan i. Eur J Nucl Med Mol Imaging. 2022 Dec;50(1):48-60. doi: 10.1007/s00259-022-05945-z. Epub 2022 Aug 24. Eur J Nucl Med Mol Imaging. 2022. PMID: 36001116
96 results