Igea A - Search Results

1

Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway.

González L, Díaz L, Pous J, Baginski B, Duran-Corbera A, Scarpa M, Brun-Heath I, Igea A, Martin-Malpartida P, Ruiz L, Pallara C, Esguerra M, Colizzi F, Mayor-Ruiz C, Biondi RM, Soliva R, Macias MJ, Orozco M, Nebreda AR. González L, et al. Among authors: igea a. Nat Commun. 2023 Jun 12;14(1):3318. doi: 10.1038/s41467-023-39051-x. Nat Commun. 2023. PMID: 37308482 Free PMC article.

2

The Stress Kinase p38α as a Target for Cancer Therapy.

Igea A, Nebreda AR. Igea A, et al. Cancer Res. 2015 Oct 1;75(19):3997-4002. doi: 10.1158/0008-5472.CAN-15-0173. Epub 2015 Sep 16. Cancer Res. 2015. PMID: 26377941 Review.

3

Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK.

Pereira L, Igea A, Canovas B, Dolado I, Nebreda AR. Pereira L, et al. Among authors: igea a. EMBO Mol Med. 2013 Nov;5(11):1759-74. doi: 10.1002/emmm.201302732. Epub 2013 Sep 24. EMBO Mol Med. 2013. PMID: 24115572 Free PMC article.

4

Regulation of tumor angiogenesis and mesenchymal-endothelial transition by p38α through TGF-β and JNK signaling.

Batlle R, Andrés E, Gonzalez L, Llonch E, Igea A, Gutierrez-Prat N, Berenguer-Llergo A, Nebreda AR. Batlle R, et al. Among authors: igea a. Nat Commun. 2019 Jul 11;10(1):3071. doi: 10.1038/s41467-019-10946-y. Nat Commun. 2019. PMID: 31296856 Free PMC article.

5

Targeting of non-oncogene addiction.

Igea A, Gupta J, Nebreda AR. Igea A, et al. Aging (Albany NY). 2015 Aug;7(8):525-6. doi: 10.18632/aging.100796. Aging (Albany NY). 2015. PMID: 26298432 Free PMC article. No abstract available.

6

Essential role of the Cdk2 activator RingoA in meiotic telomere tethering to the nuclear envelope.

Mikolcevic P, Isoda M, Shibuya H, del Barco Barrantes I, Igea A, Suja JA, Shackleton S, Watanabe Y, Nebreda AR. Mikolcevic P, et al. Among authors: igea a. Nat Commun. 2016 Mar 30;7:11084. doi: 10.1038/ncomms11084. Nat Commun. 2016. PMID: 27025256 Free PMC article.

7

Dual function of p38α MAPK in colon cancer: suppression of colitis-associated tumor initiation but requirement for cancer cell survival.

Gupta J, del Barco Barrantes I, Igea A, Sakellariou S, Pateras IS, Gorgoulis VG, Nebreda AR. Gupta J, et al. Among authors: igea a. Cancer Cell. 2014 Apr 14;25(4):484-500. doi: 10.1016/j.ccr.2014.02.019. Epub 2014 Mar 27. Cancer Cell. 2014. PMID: 24684847 Free article.

8

Quantification of Pathway Cross-talk Reveals Novel Synergistic Drug Combinations for Breast Cancer.

Jaeger S, Igea A, Arroyo R, Alcalde V, Canovas B, Orozco M, Nebreda AR, Aloy P. Jaeger S, et al. Among authors: igea a. Cancer Res. 2017 Jan 15;77(2):459-469. doi: 10.1158/0008-5472.CAN-16-0097. Epub 2016 Nov 22. Cancer Res. 2017. PMID: 27879272

9

Regulation of Mammary Luminal Cell Fate and Tumorigenesis by p38α.

Del Barco Barrantes I, Stephan-Otto Attolini C, Slobodnyuk K, Igea A, Gregorio S, Gawrzak S, Gomis RR, Nebreda AR. Del Barco Barrantes I, et al. Among authors: igea a. Stem Cell Reports. 2018 Jan 9;10(1):257-271. doi: 10.1016/j.stemcr.2017.11.021. Epub 2017 Dec 28. Stem Cell Reports. 2018. PMID: 29290625 Free PMC article.

10

Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells.

Cánovas B, Igea A, Sartori AA, Gomis RR, Paull TT, Isoda M, Pérez-Montoyo H, Serra V, González-Suárez E, Stracker TH, Nebreda AR. Cánovas B, et al. Among authors: igea a. Cancer Cell. 2018 Jun 11;33(6):1094-1110.e8. doi: 10.1016/j.ccell.2018.04.010. Epub 2018 May 24. Cancer Cell. 2018. PMID: 29805078 Free article.

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