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KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.
Hinohara K, Wu HJ, Vigneau S, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales SC, Lal-Nag M, Rai G, Maloney DJ, Jadhav A, Simeonov A, Wagle N, Brown M, Meissner A, Sicinski P, Jaffe JD, Jeselsohn R, Gimelbrant AA, Michor F, Polyak K. Hinohara K, et al. Among authors: igarashi kj. Cancer Cell. 2018 Dec 10;34(6):939-953.e9. doi: 10.1016/j.ccell.2018.10.014. Epub 2018 Nov 21. Cancer Cell. 2018. PMID: 30472020 Free PMC article.
KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.
Hinohara K, Wu HJ, Sébastien Vigneau, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales SC, Lal-Nag M, Rai G, Maloney DJ, Jadhav A, Simeonov A, Wagle N, Brown M, Meissner A, Sicinski P, Jaffe JD, Jeselsohn R, Gimelbrant AA, Michor F, Polyak K. Hinohara K, et al. Among authors: igarashi kj. Cancer Cell. 2019 Feb 11;35(2):330-332. doi: 10.1016/j.ccell.2019.01.012. Cancer Cell. 2019. PMID: 30753830 Free PMC article. No abstract available.
iPSC-derived hypoimmunogenic tissue resident memory T cells mediate robust anti-tumor activity against cervical cancer.
Furukawa Y, Ishii M, Ando J, Ikeda K, Igarashi KJ, Kinoshita S, Azusawa Y, Toyota T, Honda T, Nakanishi M, Ohshima K, Masuda A, Yoshida E, Kitade M, Porteus M, Terao Y, Nakauchi H, Ando M. Furukawa Y, et al. Among authors: igarashi kj. Cell Rep Med. 2023 Dec 19;4(12):101327. doi: 10.1016/j.xcrm.2023.101327. Epub 2023 Dec 12. Cell Rep Med. 2023. PMID: 38091985 Free PMC article.
Physioxia improves the selectivity of hematopoietic stem cell expansion cultures.
Igarashi KJ, Kucinski I, Chan YY, Tan TK, Khoo HM, Kealy D, Bhadury J, Hsu I, Ho PY, Niizuma K, Hickey JW, Nolan GP, Bridge KS, Czechowicz A, Gottgens B, Nakauchi H, Wilkinson AC. Igarashi KJ, et al. Blood Adv. 2023 Jul 25;7(14):3366-3377. doi: 10.1182/bloodadvances.2023009668. Blood Adv. 2023. PMID: 36809781 Free PMC article.
Identification and characterization of in vitro expanded hematopoietic stem cells.
Che JLC, Bode D, Kucinski I, Cull AH, Bain F, Becker HJ, Jassinskaja M, Barile M, Boyd G, Belmonte M, Zeng AGX, Igarashi KJ, Rubio-Lara J, Shepherd MS, Clay A, Dick JE, Wilkinson AC, Nakauchi H, Yamazaki S, Göttgens B, Kent DG. Che JLC, et al. Among authors: igarashi kj. EMBO Rep. 2022 Oct 6;23(10):e55502. doi: 10.15252/embr.202255502. Epub 2022 Aug 16. EMBO Rep. 2022. PMID: 35971894 Free PMC article.
Haematopoietic stem cell self-renewal in vivo and ex vivo.
Wilkinson AC, Igarashi KJ, Nakauchi H. Wilkinson AC, et al. Among authors: igarashi kj. Nat Rev Genet. 2020 Sep;21(9):541-554. doi: 10.1038/s41576-020-0241-0. Epub 2020 May 28. Nat Rev Genet. 2020. PMID: 32467607 Free PMC article. Review.
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