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Page 1
Human ZBP1 induces cell death-independent inflammatory signaling via RIPK3 and RIPK1.
Peng R, Wang CK, Wang-Kan X, Idorn M, Kjaer M, Zhou FY, Fiil BK, Timmermann F, Orozco SL, McCarthy J, Leung CS, Lu X, Bagola K, Rehwinkel J, Oberst A, Maelfait J, Paludan SR, Gyrd-Hansen M. Peng R, et al. Among authors: idorn m. EMBO Rep. 2022 Dec 6;23(12):e55839. doi: 10.15252/embr.202255839. Epub 2022 Oct 21. EMBO Rep. 2022. PMID: 36268590 Free PMC article.
SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate.
Olagnier D, Farahani E, Thyrsted J, Blay-Cadanet J, Herengt A, Idorn M, Hait A, Hernaez B, Knudsen A, Iversen MB, Schilling M, Jørgensen SE, Thomsen M, Reinert LS, Lappe M, Hoang HD, Gilchrist VH, Hansen AL, Ottosen R, Nielsen CG, Møller C, van der Horst D, Peri S, Balachandran S, Huang J, Jakobsen M, Svenningsen EB, Poulsen TB, Bartsch L, Thielke AL, Luo Y, Alain T, Rehwinkel J, Alcamí A, Hiscott J, Mogensen TH, Paludan SR, Holm CK. Olagnier D, et al. Among authors: idorn m. Nat Commun. 2020 Oct 2;11(1):4938. doi: 10.1038/s41467-020-18764-3. Nat Commun. 2020. PMID: 33009401 Free PMC article.
Author Correction: SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate.
Olagnier D, Farahani E, Thyrsted J, Blay-Cadanet J, Herengt A, Idorn M, Hait A, Hernaez B, Knudsen A, Iversen MB, Schilling M, Jørgensen SE, Thomsen M, Reinert LS, Lappe M, Hoang HD, Gilchrist VH, Hansen AL, Ottosen R, Nielsen CG, Møller C, van der Horst D, Peri S, Balachandran S, Huang J, Jakobsen M, Svenningsen EB, Poulsen TB, Bartsch L, Thielke AL, Luo Y, Alain T, Rehwinkel J, Alcamí A, Hiscott J, Mogensen TH, Paludan SR, Holm CK. Olagnier D, et al. Among authors: idorn m. Nat Commun. 2020 Oct 21;11(1):5419. doi: 10.1038/s41467-020-19363-y. Nat Commun. 2020. PMID: 33087717 Free PMC article.
Ionophore antibiotic X-206 is a potent inhibitor of SARS-CoV-2 infection in vitro.
Svenningsen EB, Thyrsted J, Blay-Cadanet J, Liu H, Lin S, Moyano-Villameriel J, Olagnier D, Idorn M, Paludan SR, Holm CK, Poulsen TB. Svenningsen EB, et al. Among authors: idorn m. Antiviral Res. 2021 Jan;185:104988. doi: 10.1016/j.antiviral.2020.104988. Epub 2020 Nov 25. Antiviral Res. 2021. PMID: 33248195 Free PMC article.
SARS-CoV-2 Neutralizing Antibody Responses towards Full-Length Spike Protein and the Receptor-Binding Domain.
Bayarri-Olmos R, Idorn M, Rosbjerg A, Pérez-Alós L, Hansen CB, Johnsen LB, Helgstrand C, Zosel F, Bjelke JR, Öberg FK, Søgaard M, Paludan SR, Bak-Thomsen T, Jardine JG, Skjoedt MO, Garred P. Bayarri-Olmos R, et al. Among authors: idorn m. J Immunol. 2021 Aug 1;207(3):878-887. doi: 10.4049/jimmunol.2100272. Epub 2021 Jul 23. J Immunol. 2021. PMID: 34301847
The alpha/B.1.1.7 SARS-CoV-2 variant exhibits significantly higher affinity for ACE-2 and requires lower inoculation doses to cause disease in K18-hACE2 mice.
Bayarri-Olmos R, Johnsen LB, Idorn M, Reinert LS, Rosbjerg A, Vang S, Hansen CB, Helgstrand C, Bjelke JR, Bak-Thomsen T, Paludan SR, Garred P, Skjoedt MO. Bayarri-Olmos R, et al. Among authors: idorn m. Elife. 2021 Nov 25;10:e70002. doi: 10.7554/eLife.70002. Elife. 2021. PMID: 34821555 Free PMC article.
TLR2 and TLR7 mediate distinct immunopathological and antiviral plasmacytoid dendritic cell responses to SARS-CoV-2 infection.
van der Sluis RM, Cham LB, Gris-Oliver A, Gammelgaard KR, Pedersen JG, Idorn M, Ahmadov U, Hernandez SS, Cémalovic E, Godsk SH, Thyrsted J, Gunst JD, Nielsen SD, Jørgensen JJ, Bjerg TW, Laustsen A, Reinert LS, Olagnier D, Bak RO, Kjolby M, Holm CK, Tolstrup M, Paludan SR, Kristensen LS, Søgaard OS, Jakobsen MR. van der Sluis RM, et al. Among authors: idorn m. EMBO J. 2022 May 16;41(10):e109622. doi: 10.15252/embj.2021109622. Epub 2022 Mar 1. EMBO J. 2022. PMID: 35178710 Free PMC article.
A Capsid Virus-Like Particle-Based SARS-CoV-2 Vaccine Induces High Levels of Antibodies and Protects Rhesus Macaques.
Volkmann A, Koopman G, Mooij P, Verschoor EJ, Verstrepen BE, Bogers WMJM, Idorn M, Paludan SR, Vang S, Nielsen MA, Sander AF, Schmittwolf C, Hochrein H, Chaplin P. Volkmann A, et al. Among authors: idorn m. Front Immunol. 2022 Apr 5;13:857440. doi: 10.3389/fimmu.2022.857440. eCollection 2022. Front Immunol. 2022. PMID: 35479095 Free PMC article.
Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity.
Fougeroux C, Goksøyr L, Idorn M, Soroka V, Myeni SK, Dagil R, Janitzek CM, Søgaard M, Aves KL, Horsted EW, Erdoğan SM, Gustavsson T, Dorosz J, Clemmensen S, Fredsgaard L, Thrane S, Vidal-Calvo EE, Khalifé P, Hulen TM, Choudhary S, Theisen M, Singh SK, Garcia-Senosiain A, Van Oosten L, Pijlman G, Hierzberger B, Domeyer T, Nalewajek BW, Strøbæk A, Skrzypczak M, Andersson LF, Buus S, Buus AS, Christensen JP, Dalebout TJ, Iversen K, Harritshøj LH, Mordmüller B, Ullum H, Reinert LS, de Jongh WA, Kikkert M, Paludan SR, Theander TG, Nielsen MA, Salanti A, Sander AF. Fougeroux C, et al. Among authors: idorn m. Nat Commun. 2021 Jan 12;12(1):324. doi: 10.1038/s41467-020-20251-8. Nat Commun. 2021. PMID: 33436573 Free PMC article.
41 results