Iding H - Search Results

1

Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors.

Haider A, Gobbi L, Kretz J, Ullmer C, Brink A, Honer M, Woltering TJ, Muri D, Iding H, Bürkler M, Binder M, Bartelmus C, Knuesel I, Pacher P, Herde AM, Spinelli F, Ahmed H, Atz K, Keller C, Weber M, Schibli R, Mu L, Grether U, Ametamey SM. Haider A, et al. Among authors: iding h. J Med Chem. 2020 Sep 24;63(18):10287-10306. doi: 10.1021/acs.jmedchem.0c00778. Epub 2020 Sep 1. J Med Chem. 2020. PMID: 32787079

2

Identification of potent and selective cathepsin S inhibitors containing different central cyclic scaffolds.

Hilpert H, Mauser H, Humm R, Anselm L, Kuehne H, Hartmann G, Gruener S, Banner DW, Benz J, Gsell B, Kuglstatter A, Stihle M, Thoma R, Sanchez RA, Iding H, Wirz B, Haap W. Hilpert H, et al. Among authors: iding h. J Med Chem. 2013 Dec 12;56(23):9789-801. doi: 10.1021/jm401528k. Epub 2013 Nov 22. J Med Chem. 2013. PMID: 24224654

3

New, efficient synthesis of oseltamivir phosphate (Tamiflu) via enzymatic desymmetrization of a meso-1,3-cyclohexanedicarboxylic acid diester.

Zutter U, Iding H, Spurr P, Wirz B. Zutter U, et al. Among authors: iding h. J Org Chem. 2008 Jul 4;73(13):4895-902. doi: 10.1021/jo800264d. Epub 2008 Jun 3. J Org Chem. 2008. PMID: 18517254

4

Towards the enzymatic synthesis of phosphorothioate containing LNA oligonucleotides.

Flamme M, Hanlon S, Iding H, Puentener K, Sladojevich F, Hollenstein M. Flamme M, et al. Among authors: iding h. Bioorg Med Chem Lett. 2021 Sep 15;48:128242. doi: 10.1016/j.bmcl.2021.128242. Epub 2021 Jul 1. Bioorg Med Chem Lett. 2021. PMID: 34217829 Free article.

5

Synthesis of enantiomerically pure [¹⁴ C]-labelled morpholine derivatives for a class of trace amine-associate receptor 1 agonists.

Edelmann MR, Hartung T, Trussardi R, Iding H, Galley G, Pflieger P, Norcross RD. Edelmann MR, et al. Among authors: iding h. J Labelled Comp Radiopharm. 2016 Dec;59(14):635-639. doi: 10.1002/jlcr.3403. Epub 2016 May 15. J Labelled Comp Radiopharm. 2016. PMID: 27196363

6

Stereoselective Synthesis of the IDO Inhibitor Navoximod.

St-Jean F, Angelaud R, Bachmann S, Carrera DE, Remarchuk T, Piechowicz KA, Niedermann K, Iding H, Meier R, Hou H, Sirois LE, Xu J, Olbrich M, Rege P, Guillemot-Plass M, Gosselin F. St-Jean F, et al. Among authors: iding h. J Org Chem. 2022 Apr 1;87(7):4955-4960. doi: 10.1021/acs.joc.1c02994. Epub 2022 Mar 23. J Org Chem. 2022. PMID: 35317556

7

Effective engineering of a ketoreductase for the biocatalytic synthesis of an ipatasertib precursor.

Honda Malca S, Duss N, Meierhofer J, Patsch D, Niklaus M, Reiter S, Hanlon SP, Wetzl D, Kuhn B, Iding H, Buller R. Honda Malca S, et al. Among authors: iding h. Commun Chem. 2024 Feb 28;7(1):46. doi: 10.1038/s42004-024-01130-5. Commun Chem. 2024. PMID: 38418529 Free PMC article.

8

Protein-engineering of an amine transaminase for the stereoselective synthesis of a pharmaceutically relevant bicyclic amine.

Weiß MS, Pavlidis IV, Spurr P, Hanlon SP, Wirz B, Iding H, Bornscheuer UT. Weiß MS, et al. Among authors: iding h. Org Biomol Chem. 2016 Nov 2;14(43):10249-10254. doi: 10.1039/c6ob02139e. Org Biomol Chem. 2016. PMID: 27739550

9

Expanding the Imine Reductase Toolbox by Exploring the Bacterial Protein-Sequence Space.

Wetzl D, Berrera M, Sandon N, Fishlock D, Ebeling M, Müller M, Hanlon S, Wirz B, Iding H. Wetzl D, et al. Among authors: iding h. Chembiochem. 2015 Aug 17;16(12):1749-56. doi: 10.1002/cbic.201500218. Epub 2015 Jul 2. Chembiochem. 2015. PMID: 26044455

10

Identification of (S)-selective transaminases for the asymmetric synthesis of bulky chiral amines.

Pavlidis IV, Weiß MS, Genz M, Spurr P, Hanlon SP, Wirz B, Iding H, Bornscheuer UT. Pavlidis IV, et al. Among authors: iding h. Nat Chem. 2016 Nov;8(11):1076-1082. doi: 10.1038/nchem.2578. Epub 2016 Jul 18. Nat Chem. 2016. PMID: 27768108

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