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A consortium-driven framework to guide the implementation of ICH M7 Option 4 control strategies.
Barber C, Antonucci V, Baumann JC, Brown R, Covey-Crump E, Elder D, Elliott E, Fennell JW, Gallou F, Ide ND, Jordine G, Kallemeyn JM, Lauwers D, Looker AR, Lovelle LE, McLaughlin M, Molzahn R, Ott M, Schils D, Oestrich RS, Stevenson N, Talavera P, Teasdale A, Urquhart MW, Varie DL, Welch D. Barber C, et al. Among authors: ide nd. Regul Toxicol Pharmacol. 2017 Nov;90:22-28. doi: 10.1016/j.yrtph.2017.08.008. Epub 2017 Aug 16. Regul Toxicol Pharmacol. 2017. PMID: 28822875
Synthesis of ABBV-168, a 2'-Bromouridine for the Treatment of Hepatitis C.
Voight EA, Brown BS, Greszler SN, Halvorsen GT, Zhao G, Kruger AW, Hartung J, Lukin KA, Martinez SR, Moschetta EG, Tudesco MT, Ide ND. Voight EA, et al. Among authors: ide nd. J Org Chem. 2019 Apr 19;84(8):4723-4734. doi: 10.1021/acs.joc.8b02341. Epub 2018 Nov 19. J Org Chem. 2019. PMID: 30412402