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Nitric oxide facilitates the targeting Kupffer cells of a nano-antioxidant for the treatment of NASH.
Maeda H, Ishima Y, Saruwatari J, Mizuta Y, Minayoshi Y, Ichimizu S, Yanagisawa H, Nagasaki T, Yasuda K, Oshiro S, Taura M, McConnell MJ, Oniki K, Sonoda K, Wakayama T, Kinoshita M, Shuto T, Kai H, Tanaka M, Sasaki Y, Iwakiri Y, Otagiri M, Watanabe H, Maruyama T. Maeda H, et al. Among authors: ichimizu s. J Control Release. 2022 Jan;341:457-474. doi: 10.1016/j.jconrel.2021.11.039. Epub 2021 Nov 29. J Control Release. 2022. PMID: 34856227
Design and tuning of a cell-penetrating albumin derivative as a versatile nanovehicle for intracellular drug delivery.
Ichimizu S, Watanabe H, Maeda H, Hamasaki K, Nakamura Y, Chuang VTG, Kinoshita R, Nishida K, Tanaka R, Enoki Y, Ishima Y, Kuniyasu A, Kobashigawa Y, Morioka H, Futaki S, Otagiri M, Maruyama T. Ichimizu S, et al. J Control Release. 2018 May 10;277:23-34. doi: 10.1016/j.jconrel.2018.02.037. Epub 2018 Mar 10. J Control Release. 2018. PMID: 29530390
Cell-penetrating mechanism of intracellular targeting albumin: Contribution of macropinocytosis induction and endosomal escape.
Ichimizu S, Watanabe H, Maeda H, Hamasaki K, Ikegami K, Chuang VTG, Kinoshita R, Nishida K, Shimizu T, Ishima Y, Ishida T, Seki T, Katsuki H, Futaki S, Otagiri M, Maruyama T. Ichimizu S, et al. J Control Release. 2019 Jun 28;304:156-163. doi: 10.1016/j.jconrel.2019.05.015. Epub 2019 May 10. J Control Release. 2019. PMID: 31082432