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N-Acetylcysteine Alters Disease Progression and Increases Janus Kinase Mutation Frequency in a Mouse Model of Precursor B-Cell Acute Lymphoblastic Leukemia.
J Pharmacol Exp Ther. 2024 Mar 15;389(1):40-50. doi: 10.1124/jpet.123.002000.
J Pharmacol Exp Ther. 2024.
PMID: 38336380
IKZF3/Aiolos H195Y mutation identified in a mouse model of B cell leukemia results in altered DNA binding and altered STAT5-dependent gene expression.
Rodrigues de Oliveira B, Iansavitchous J, Rysan H, Wang WC, Sams MP, Knight D, Xu LS, Jeong J, Qu TP, Zorzi AP, DeKoter RP.
Rodrigues de Oliveira B, et al. Among authors: iansavitchous j.
Gene. 2024 Mar 30;900:148131. doi: 10.1016/j.gene.2024.148131. Epub 2024 Jan 10.
Gene. 2024.
PMID: 38216003
Free article.
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Janus Kinase Mutations in Mice Lacking PU.1 and Spi-B Drive B Cell Leukemia through Reactive Oxygen Species-Induced DNA Damage.
Lim M, Batista CR, de Oliveira BR, Creighton R, Ferguson J, Clemmer K, Knight D, Iansavitchous J, Mahmood D, Avino M, DeKoter RP.
Lim M, et al. Among authors: iansavitchous j.
Mol Cell Biol. 2020 Aug 28;40(18):e00189-20. doi: 10.1128/MCB.00189-20. Print 2020 Aug 28.
Mol Cell Biol. 2020.
PMID: 32631903
Free PMC article.
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