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2-Azo-, 2-diazocine-thiazols and 2-azo-imidazoles as photoswitchable kinase inhibitors: limitations and pitfalls of the photoswitchable inhibitor approach.
Photochem Photobiol Sci. 2019 Jun 12;18(6):1398-1407. doi: 10.1039/c9pp00010k.
Photochem Photobiol Sci. 2019.
PMID: 30924488
Optimized 4,5-Diarylimidazoles as Potent/Selective Inhibitors of Protein Kinase CK1δ and Their Structural Relation to p38α MAPK.
Halekotte J, Witt L, Ianes C, Krüger M, Bührmann M, Rauh D, Pichlo C, Brunstein E, Luxenburger A, Baumann U, Knippschild U, Bischof J, Peifer C.
Halekotte J, et al. Among authors: ianes c.
Molecules. 2017 Mar 24;22(4):522. doi: 10.3390/molecules22040522.
Molecules. 2017.
PMID: 28338621
Free PMC article.
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Design, Synthesis and Biological Evaluation of Isoxazole-Based CK1 Inhibitors Modified with Chiral Pyrrolidine Scaffolds.
Luxenburger A, Schmidt D, Ianes C, Pichlo C, Krüger M, von Drathen T, Brunstein E, Gainsford GJ, Baumann U, Knippschild U, Peifer C.
Luxenburger A, et al. Among authors: ianes c.
Molecules. 2019 Mar 1;24(5):873. doi: 10.3390/molecules24050873.
Molecules. 2019.
PMID: 30832206
Free PMC article.
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Newly Developed CK1-Specific Inhibitors Show Specifically Stronger Effects on CK1 Mutants and Colon Cancer Cell Lines.
Liu C, Witt L, Ianes C, Bischof J, Bammert MT, Baier J, Kirschner S, Henne-Bruns D, Xu P, Kornmann M, Peifer C, Knippschild U.
Liu C, et al. Among authors: ianes c.
Int J Mol Sci. 2019 Dec 7;20(24):6184. doi: 10.3390/ijms20246184.
Int J Mol Sci. 2019.
PMID: 31817920
Free PMC article.
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Structure, regulation, and (patho-)physiological functions of the stress-induced protein kinase CK1 delta (CSNK1D).
Xu P, Ianes C, Gärtner F, Liu C, Burster T, Bakulev V, Rachidi N, Knippschild U, Bischof J.
Xu P, et al. Among authors: ianes c.
Gene. 2019 Oct 5;715:144005. doi: 10.1016/j.gene.2019.144005. Epub 2019 Jul 31.
Gene. 2019.
PMID: 31376410
Free PMC article.
Review.
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CK1δ activity is modulated by CDK2/E- and CDK5/p35-mediated phosphorylation.
Ianes C, Xu P, Werz N, Meng Z, Henne-Bruns D, Bischof J, Knippschild U.
Ianes C, et al.
Amino Acids. 2016 Feb;48(2):579-92. doi: 10.1007/s00726-015-2114-y.
Amino Acids. 2016.
PMID: 26464264
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CK1δ kinase activity is modulated by protein kinase C α (PKCα)-mediated site-specific phosphorylation.
Meng Z, Bischof J, Ianes C, Henne-Bruns D, Xu P, Knippschild U.
Meng Z, et al. Among authors: ianes c.
Amino Acids. 2016 May;48(5):1185-97. doi: 10.1007/s00726-015-2154-3. Epub 2016 Jan 23.
Amino Acids. 2016.
PMID: 26803658
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