Iancu O - Search Results

1

Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients.

Hassin O, Nataraj NB, Shreberk-Shaked M, Aylon Y, Yaeger R, Fontemaggi G, Mukherjee S, Maddalena M, Avioz A, Iancu O, Mallel G, Gershoni A, Grosheva I, Feldmesser E, Ben-Dor S, Golani O, Hendel A, Blandino G, Kelsen D, Yarden Y, Oren M. Hassin O, et al. Among authors: iancu o. Nat Commun. 2022 May 19;13(1):2800. doi: 10.1038/s41467-022-30481-7. Nat Commun. 2022. PMID: 35589715 Free PMC article.

2

Increasing CRISPR Efficiency and Measuring Its Specificity in HSPCs Using a Clinically Relevant System.

Shapiro J, Iancu O, Jacobi AM, McNeill MS, Turk R, Rettig GR, Amit I, Tovin-Recht A, Yakhini Z, Behlke MA, Hendel A. Shapiro J, et al. Among authors: iancu o. Mol Ther Methods Clin Dev. 2020 May 4;17:1097-1107. doi: 10.1016/j.omtm.2020.04.027. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2020. PMID: 32478125 Free PMC article.

3

Chemical Modification of Guide RNAs for Improved CRISPR Activity in CD34+ Human Hematopoietic Stem and Progenitor Cells.

Shapiro J, Tovin A, Iancu O, Allen D, Hendel A. Shapiro J, et al. Among authors: iancu o. Methods Mol Biol. 2021;2162:37-48. doi: 10.1007/978-1-0716-0687-2_3. Methods Mol Biol. 2021. PMID: 32926376

4

CRISPECTOR provides accurate estimation of genome editing translocation and off-target activity from comparative NGS data.

Amit I, Iancu O, Levy-Jurgenson A, Kurgan G, McNeill MS, Rettig GR, Allen D, Breier D, Ben Haim N, Wang Y, Anavy L, Hendel A, Yakhini Z. Amit I, et al. Among authors: iancu o. Nat Commun. 2021 May 24;12(1):3042. doi: 10.1038/s41467-021-22417-4. Nat Commun. 2021. PMID: 34031394 Free PMC article.

5

Microfluidic tool for rapid functional characterization of CRISPR complexes.

Peleg-Chen D, Shuvali G, Brio L, Ifrach A, Iancu O, Barbiro-Michaely E, Hendel A, Gerber D. Peleg-Chen D, et al. Among authors: iancu o. N Biotechnol. 2022 May 25;68:1-8. doi: 10.1016/j.nbt.2022.01.003. Epub 2022 Jan 10. N Biotechnol. 2022. PMID: 35026470 Free PMC article.

6

High-Throughput Imaging of CRISPR- and Recombinant Adeno-Associated Virus-Induced DNA Damage Response in Human Hematopoietic Stem and Progenitor Cells.

Allen D, Weiss LE, Saguy A, Rosenberg M, Iancu O, Matalon O, Lee C, Beider K, Nagler A, Shechtman Y, Hendel A. Allen D, et al. Among authors: iancu o. CRISPR J. 2022 Feb;5(1):80-94. doi: 10.1089/crispr.2021.0128. Epub 2022 Jan 20. CRISPR J. 2022. PMID: 35049367 Free PMC article.

7

Multiplex HDR for disease and correction modeling of SCID by CRISPR genome editing in human HSPCs.

Iancu O, Allen D, Knop O, Zehavi Y, Breier D, Arbiv A, Lev A, Lee YN, Beider K, Nagler A, Somech R, Hendel A. Iancu O, et al. Mol Ther Nucleic Acids. 2022 Dec 9;31:105-121. doi: 10.1016/j.omtn.2022.12.006. eCollection 2023 Mar 14. Mol Ther Nucleic Acids. 2022. PMID: 36618262 Free PMC article.

8

CRISPR-Cas9 engineering of the RAG2 locus via complete coding sequence replacement for therapeutic applications.

Allen D, Knop O, Itkowitz B, Kalter N, Rosenberg M, Iancu O, Beider K, Lee YN, Nagler A, Somech R, Hendel A. Allen D, et al. Among authors: iancu o. Nat Commun. 2023 Oct 27;14(1):6771. doi: 10.1038/s41467-023-42036-5. Nat Commun. 2023. PMID: 37891182 Free PMC article.

9

WWOX and p53 Dysregulation Synergize to Drive the Development of Osteosarcoma.

Del Mare S, Husanie H, Iancu O, Abu-Odeh M, Evangelou K, Lovat F, Volinia S, Gordon J, Amir G, Stein J, Stein GS, Croce CM, Gorgoulis V, Lian JB, Aqeilan RI. Del Mare S, et al. Among authors: iancu o. Cancer Res. 2016 Oct 15;76(20):6107-6117. doi: 10.1158/0008-5472.CAN-16-0621. Epub 2016 Aug 22. Cancer Res. 2016. PMID: 27550453 Free PMC article.

10

Distribution and Behaviour of Some Trace Elements as a Function of Apple Varieties in Northeastern Romania.

Prundeanu IM, Chelariu C, Balaban SI, Iancu OG. Prundeanu IM, et al. Among authors: iancu og. Int J Environ Res Public Health. 2020 Apr 10;17(7):2607. doi: 10.3390/ijerph17072607. Int J Environ Res Public Health. 2020. PMID: 32290204 Free PMC article.

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