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Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells.
Patsch C, Challet-Meylan L, Thoma EC, Urich E, Heckel T, O'Sullivan JF, Grainger SJ, Kapp FG, Sun L, Christensen K, Xia Y, Florido MH, He W, Pan W, Prummer M, Warren CR, Jakob-Roetne R, Certa U, Jagasia R, Freskgård PO, Adatto I, Kling D, Huang P, Zon LI, Chaikof EL, Gerszten RE, Graf M, Iacone R, Cowan CA. Patsch C, et al. Among authors: iacone r. Nat Cell Biol. 2015 Aug;17(8):994-1003. doi: 10.1038/ncb3205. Epub 2015 Jul 27. Nat Cell Biol. 2015. PMID: 26214132 Free PMC article.
Chemical conversion of human fibroblasts into functional Schwann cells.
Thoma EC, Merkl C, Heckel T, Haab R, Knoflach F, Nowaczyk C, Flint N, Jagasia R, Jensen Zoffmann S, Truong HH, Petitjean P, Jessberger S, Graf M, Iacone R. Thoma EC, et al. Among authors: iacone r. Stem Cell Reports. 2014 Oct 14;3(4):539-47. doi: 10.1016/j.stemcr.2014.07.014. Epub 2014 Sep 11. Stem Cell Reports. 2014. PMID: 25358782 Free PMC article.
Disease modeling and phenotypic drug screening for diabetic cardiomyopathy using human induced pluripotent stem cells.
Drawnel FM, Boccardo S, Prummer M, Delobel F, Graff A, Weber M, Gérard R, Badi L, Kam-Thong T, Bu L, Jiang X, Hoflack JC, Kiialainen A, Jeworutzki E, Aoyama N, Carlson C, Burcin M, Gromo G, Boehringer M, Stahlberg H, Hall BJ, Magnone MC, Kolaja K, Chien KR, Bailly J, Iacone R. Drawnel FM, et al. Among authors: iacone r. Cell Rep. 2014 Nov 6;9(3):810-21. doi: 10.1016/j.celrep.2014.09.055. Epub 2014 Oct 30. Cell Rep. 2014. PMID: 25437537 Free article.
Generation of functional podocytes from human induced pluripotent stem cells.
Ciampi O, Iacone R, Longaretti L, Benedetti V, Graf M, Magnone MC, Patsch C, Xinaris C, Remuzzi G, Benigni A, Tomasoni S. Ciampi O, et al. Among authors: iacone r. Stem Cell Res. 2016 Jul;17(1):130-9. doi: 10.1016/j.scr.2016.06.001. Epub 2016 Jun 3. Stem Cell Res. 2016. PMID: 27299470 Free PMC article.
Molecular Phenotyping Combines Molecular Information, Biological Relevance, and Patient Data to Improve Productivity of Early Drug Discovery.
Drawnel FM, Zhang JD, Küng E, Aoyama N, Benmansour F, Araujo Del Rosario A, Jensen Zoffmann S, Delobel F, Prummer M, Weibel F, Carlson C, Anson B, Iacone R, Certa U, Singer T, Ebeling M, Prunotto M. Drawnel FM, et al. Among authors: iacone r. Cell Chem Biol. 2017 May 18;24(5):624-634.e3. doi: 10.1016/j.chembiol.2017.03.016. Epub 2017 Apr 20. Cell Chem Biol. 2017. PMID: 28434878 Free article.
A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.
Ding L, Paszkowski-Rogacz M, Nitzsche A, Slabicki MM, Heninger AK, de Vries I, Kittler R, Junqueira M, Shevchenko A, Schulz H, Hubner N, Doss MX, Sachinidis A, Hescheler J, Iacone R, Anastassiadis K, Stewart AF, Pisabarro MT, Caldarelli A, Poser I, Theis M, Buchholz F. Ding L, et al. Among authors: iacone r. Cell Stem Cell. 2009 May 8;4(5):403-15. doi: 10.1016/j.stem.2009.03.009. Epub 2009 Apr 2. Cell Stem Cell. 2009. PMID: 19345177 Free article.
A short G1 phase is an intrinsic determinant of naïve embryonic stem cell pluripotency.
Coronado D, Godet M, Bourillot PY, Tapponnier Y, Bernat A, Petit M, Afanassieff M, Markossian S, Malashicheva A, Iacone R, Anastassiadis K, Savatier P. Coronado D, et al. Among authors: iacone r. Stem Cell Res. 2013 Jan;10(1):118-31. doi: 10.1016/j.scr.2012.10.004. Epub 2012 Oct 29. Stem Cell Res. 2013. PMID: 23178806 Free article.
Nanog induces hyperplasia without initiating tumors.
Fischedick G, Wu G, Adachi K, Araúzo-Bravo MJ, Greber B, Radstaak M, Köhler G, Tapia N, Iacone R, Anastassiadis K, Schöler HR, Zaehres H. Fischedick G, et al. Among authors: iacone r. Stem Cell Res. 2014 Sep;13(2):300-15. doi: 10.1016/j.scr.2014.08.001. Epub 2014 Aug 10. Stem Cell Res. 2014. PMID: 25173648 Free article.
N-Terminomics identifies HtrA1 cleavage of thrombospondin-1 with generation of a proangiogenic fragment in the polarized retinal pigment epithelial cell model of age-related macular degeneration.
Chen CY, Melo E, Jakob P, Friedlein A, Elsässer B, Goettig P, Kueppers V, Delobel F, Stucki C, Dunkley T, Fauser S, Schilling O, Iacone R. Chen CY, et al. Among authors: iacone r. Matrix Biol. 2018 Sep;70:84-101. doi: 10.1016/j.matbio.2018.03.013. Epub 2018 Mar 20. Matrix Biol. 2018. PMID: 29572155 Free article.
97 results