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Intratumoral Injection of Large Surface Area Microparticle Taxanes in Carcinomas Increases Immune Effector Cell Concentrations, Checkpoint Expression, and Synergy with Checkpoint Inhibitors: A Review of Preclinical and Clinical Studies.
Oncol Ther. 2024 Mar;12(1):31-55. doi: 10.1007/s40487-024-00261-y. Epub 2024 Jan 30.
Oncol Ther. 2024.
PMID: 38289576
Free PMC article.
Review.
Local administration of submicron particle paclitaxel to solid carcinomas induces direct cytotoxicity and immune-mediated tumoricidal effects without local or systemic toxicity: preclinical and clinical studies.
Verco S, Maulhardt H, Baltezor M, Williams E, Iacobucci M, Wendt A, Verco J, Marin A, Campbell S, Dorman P, diZerega G.
Verco S, et al.
Drug Deliv Transl Res. 2021 Oct;11(5):1806-1817. doi: 10.1007/s13346-020-00868-4. Epub 2020 Nov 6.
Drug Deliv Transl Res. 2021.
PMID: 33159289
Free PMC article.
Review.
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Phase 1/2 study of topical submicron particle paclitaxel for cutaneous metastases of breast cancer.
Lacouture ME, Goldfarb SB, Markova A, Chawla SP, Dewnani K, Iacobucci M, Lang JE.
Lacouture ME, et al.
Breast Cancer Res Treat. 2022 Jul;194(1):57-64. doi: 10.1007/s10549-022-06584-6. Epub 2022 Apr 26.
Breast Cancer Res Treat. 2022.
PMID: 35471470
Free PMC article.
Clinical Trial.
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