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Page 1
Hepatic stellate cell stearoyl co-A desaturase activates leukotriene B4 receptor 2 - β-catenin cascade to promote liver tumorigenesis.
Sinha S, Aizawa S, Nakano Y, Rialdi A, Choi HY, Shrestha R, Pan SQ, Chen Y, Li M, Kapelanski-Lamoureux A, Yochum G, Sher L, Monga SP, Lazaris A, Machida K, Karin M, Guccione E, Tsukamoto H. Sinha S, et al. Nat Commun. 2023 May 8;14(1):2651. doi: 10.1038/s41467-023-38406-8. Nat Commun. 2023. PMID: 37156770 Free PMC article.
Comprehensive characterization of hepatocyte-derived extracellular vesicles identifies direct miRNA-based regulation of hepatic stellate cells and DAMP-based hepatic macrophage IL-1β and IL-17 upregulation in alcoholic hepatitis mice.
Eguchi A, Yan R, Pan SQ, Wu R, Kim J, Chen Y, Ansong C, Smith RD, Tempaku M, Ohno-Machado L, Takei Y, Feldstein AE, Tsukamoto H. Eguchi A, et al. J Mol Med (Berl). 2020 Jul;98(7):1021-1034. doi: 10.1007/s00109-020-01926-7. Epub 2020 Jun 18. J Mol Med (Berl). 2020. PMID: 32556367 Free PMC article.
Stearoyl-CoA desaturase and tumorigenesis.
Kikuchi K, Tsukamoto H. Kikuchi K, et al. Chem Biol Interact. 2020 Jan 25;316:108917. doi: 10.1016/j.cbi.2019.108917. Epub 2019 Dec 12. Chem Biol Interact. 2020. PMID: 31838050 Free PMC article. Review.
Cell Death and Liver Disease.
Aizawa S, Brar G, Tsukamoto H. Aizawa S, et al. Gut Liver. 2020 Jan 15;14(1):20-29. doi: 10.5009/gnl18486. Gut Liver. 2020. PMID: 30917630 Free PMC article. Review.
Summary of the 2018 Alcohol and Immunology Research Interest Group (AIRIG) meeting.
Kuprys PV, Tsukamoto H, Gao B, Jia L, McGowan J, Coopersmith CM, Moreno MC, Hulsebus H, Meena AS, Souza-Smith FM, Roper P, Foster MT, Raju SV, Marshall SA, Fujita M, Curtis BJ, Wyatt TA, Mandrekar P, Kovacs EJ, Choudhry MA. Kuprys PV, et al. Alcohol. 2019 Jun;77:11-18. doi: 10.1016/j.alcohol.2018.08.010. Epub 2018 Aug 24. Alcohol. 2019. PMID: 30763905 Free PMC article. Review.
Inflammatory pathways in alcoholic steatohepatitis.
Gao B, Ahmad MF, Nagy LE, Tsukamoto H. Gao B, et al. J Hepatol. 2019 Feb;70(2):249-259. doi: 10.1016/j.jhep.2018.10.023. J Hepatol. 2019. PMID: 30658726 Free PMC article. Review.