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Identification of a set of genes potentially responsible for resistance to ferroptosis in lung adenocarcinoma cancer stem cells.
Ascenzi F, Esposito A, Bruschini S, Salvati V, De Vitis C, De Arcangelis V, Ricci G, Catizione A, di Martino S, Buglioni S, Bassi M, Venuta F, De Nicola F, Massacci A, Grassucci I, Pallocca M, Ricci A, Fanciulli M, Ciliberto G, Mancini R. Ascenzi F, et al. Cell Death Dis. 2024 Apr 29;15(4):303. doi: 10.1038/s41419-024-06667-w. Cell Death Dis. 2024. PMID: 38684666 Free PMC article.
Upregulated expression of miR-4443 and miR-4488 in drug resistant melanomas promotes migratory and invasive phenotypes through downregulation of intermediate filament nestin.
Castaldo V, Minopoli M, Di Modugno F, Sacconi A, Liguoro D, Frigerio R, Ortolano A, Di Martile M, Gesualdi L, Madonna G, Capone M, Cirombella R, Catizone A, Del Bufalo D, Vecchione A, Carriero MV, Ascierto PA, Mancini R, Fattore L, Ciliberto G. Castaldo V, et al. J Exp Clin Cancer Res. 2023 Nov 27;42(1):317. doi: 10.1186/s13046-023-02878-9. J Exp Clin Cancer Res. 2023. PMID: 38008717 Free PMC article.
Oncosuppressive miRNAs loaded in lipid nanoparticles potentiate targeted therapies in BRAF-mutant melanoma by inhibiting core escape pathways of resistance.
Fattore L, Cafaro G, Di Martile M, Campani V, Sacconi A, Liguoro D, Marra E, Bruschini S, Stoppoloni D, Cirombella R, De Nicola F, Pallocca M, Ruggiero CF, Castaldo V, Catizone A, Del Bufalo D, Viglietto G, Vecchione A, Blandino G, Aurisicchio L, Fanciulli M, Ascierto PA, De Rosa G, Mancini R, Ciliberto G. Fattore L, et al. Oncogene. 2023 Jan;42(4):293-307. doi: 10.1038/s41388-022-02547-9. Epub 2022 Nov 23. Oncogene. 2023. PMID: 36418472 Free PMC article.
SCD1, autophagy and cancer: implications for therapy.
Ascenzi F, De Vitis C, Maugeri-Saccà M, Napoli C, Ciliberto G, Mancini R. Ascenzi F, et al. J Exp Clin Cancer Res. 2021 Aug 24;40(1):265. doi: 10.1186/s13046-021-02067-6. J Exp Clin Cancer Res. 2021. PMID: 34429143 Free PMC article. Review.
Synergistic antitumor interaction of valproic acid and simvastatin sensitizes prostate cancer to docetaxel by targeting CSCs compartment via YAP inhibition.
Iannelli F, Roca MS, Lombardi R, Ciardiello C, Grumetti L, De Rienzo S, Moccia T, Vitagliano C, Sorice A, Costantini S, Milone MR, Pucci B, Leone A, Di Gennaro E, Mancini R, Ciliberto G, Bruzzese F, Budillon A. Iannelli F, et al. J Exp Clin Cancer Res. 2020 Oct 8;39(1):213. doi: 10.1186/s13046-020-01723-7. J Exp Clin Cancer Res. 2020. PMID: 33032653 Free PMC article.
Inhibition of Stearoyl-CoA desaturase 1 reverts BRAF and MEK inhibition-induced selection of cancer stem cells in BRAF-mutated melanoma.
Pisanu ME, Maugeri-Saccà M, Fattore L, Bruschini S, De Vitis C, Tabbì E, Bellei B, Migliano E, Kovacs D, Camera E, Picardo M, Jakopin Z, Cippitelli C, Bartolazzi A, Raffa S, Torrisi MR, Fulciniti F, Ascierto PA, Ciliberto G, Mancini R. Pisanu ME, et al. J Exp Clin Cancer Res. 2018 Dec 17;37(1):318. doi: 10.1186/s13046-018-0989-7. J Exp Clin Cancer Res. 2018. PMID: 30558661 Free PMC article.