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2020 1
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2023 5
2024 1

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Page 1
Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system.
Sarma P, Carino CMC, Seetharama D, Pandey S, Dwivedi-Agnihotri H, Rui X, Cao Y, Kawakami K, Kumari P, Chen YC, Luker KE, Yadav PN, Luker GD, Laporte SA, Chen X, Inoue A, Shukla AK. Sarma P, et al. Nat Commun. 2023 Aug 9;14(1):4808. doi: 10.1038/s41467-023-40482-9. Nat Commun. 2023. PMID: 37558722 Free PMC article.
Plasma membrane preassociation drives β-arrestin coupling to receptors and activation.
Grimes J, Koszegi Z, Lanoiselée Y, Miljus T, O'Brien SL, Stepniewski TM, Medel-Lacruz B, Baidya M, Makarova M, Mistry R, Goulding J, Drube J, Hoffmann C, Owen DM, Shukla AK, Selent J, Hill SJ, Calebiro D. Grimes J, et al. Cell. 2023 May 11;186(10):2238-2255.e20. doi: 10.1016/j.cell.2023.04.018. Epub 2023 May 4. Cell. 2023. PMID: 37146613 Free PMC article.
Resonating with the signaling bias of CXCR7.
Sarma P, Shukla AK. Sarma P, et al. Mol Cell. 2022 Sep 15;82(18):3318-3320. doi: 10.1016/j.molcel.2022.08.020. Mol Cell. 2022. PMID: 36113411 Free PMC article.
Structural snapshot of a β-arrestin-biased receptor.
Sarma P, Banerjee R, Shukla AK. Sarma P, et al. Trends Pharmacol Sci. 2023 Jan;44(1):1-3. doi: 10.1016/j.tips.2022.08.005. Epub 2022 Aug 31. Trends Pharmacol Sci. 2023. PMID: 36057461 Free PMC article.
Targeting the cell's gatekeepers for novel drug discovery.
Stephens GJ, Shukla AK. Stephens GJ, et al. Br J Pharmacol. 2022 Jul;179(14):3485-3486. doi: 10.1111/bph.15831. Epub 2022 Apr 7. Br J Pharmacol. 2022. PMID: 35393664 Free PMC article. No abstract available.
18 results