I01 BX004842/BX/BLRD VA/United States[Grants and Funding] - Search Results

Year	Number of Results
2020	3
2021	7
2022	6
2023	4
2024	0

1

AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons.

Maltby CJ, Krans A, Grudzien SJ, Palacios Y, Muiños J, Suárez A, Asher M, Khurana V, Barmada SJ, Dijkstra AA, Todd PK. Maltby CJ, et al. bioRxiv [Preprint]. 2023 Dec 14:2023.12.13.571345. doi: 10.1101/2023.12.13.571345. bioRxiv. 2023. PMID: 38168171 Free PMC article. Preprint.

2

Stress granule formation helps to mitigate neurodegeneration.

Glineburg MR, Yildirim E, Gomez N, Li X, Pak J, Altheim C, Waksmacki J, McInerney G, Barmada SJ, Todd PK. Glineburg MR, et al. bioRxiv [Preprint]. 2023 Nov 11:2023.11.07.566060. doi: 10.1101/2023.11.07.566060. bioRxiv. 2023. PMID: 37986813 Free PMC article. Preprint.

3

Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats.

Tseng YJ, Malik I, Deng X, Krans A, Jansen-West K, Tank EMH, Gomez NB, Sher R, Petrucelli L, Barmada SJ, Todd PK. Tseng YJ, et al. bioRxiv [Preprint]. 2023 Jun 7:2023.06.07.544135. doi: 10.1101/2023.06.07.544135. bioRxiv. 2023. PMID: 37333274 Free PMC article. Updated. Preprint.

4

Native functions of short tandem repeats.

Wright SE, Todd PK. Wright SE, et al. Elife. 2023 Mar 20;12:e84043. doi: 10.7554/eLife.84043. Elife. 2023. PMID: 36940239 Free PMC article.

5

Repeat-Associated Non-AUG Translation of AGAGGG Repeats that Cause X-Linked Dystonia-Parkinsonism.

Reyes CJ, Asano K, Todd PK, Klein C, Rakovic A. Reyes CJ, et al. Mov Disord. 2022 Nov;37(11):2284-2289. doi: 10.1002/mds.29183. Epub 2022 Aug 16. Mov Disord. 2022. PMID: 35971992

6

CGG repeats trigger translational frameshifts that generate aggregation-prone chimeric proteins.

Wright SE, Rodriguez CM, Monroe J, Xing J, Krans A, Flores BN, Barsur V, Ivanova MI, Koutmou KS, Barmada SJ, Todd PK. Wright SE, et al. Nucleic Acids Res. 2022 Aug 26;50(15):8674-8689. doi: 10.1093/nar/gkac626. Nucleic Acids Res. 2022. PMID: 35904811 Free PMC article.

7

Identification of PSMB5 as a genetic modifier of fragile X-associated tremor/ataxia syndrome.

Kong HE, Lim J, Linsalata A, Kang Y, Malik I, Allen EG, Cao Y, Shubeck L, Johnston R, Huang Y, Gu Y, Guo X, Zwick ME, Qin Z, Wingo TS, Juncos J, Nelson DL, Epstein MP, Cutler DJ, Todd PK, Sherman SL, Warren ST, Jin P. Kong HE, et al. Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2118124119. doi: 10.1073/pnas.2118124119. Epub 2022 May 26. Proc Natl Acad Sci U S A. 2022. PMID: 35617426 Free PMC article.

8

Non-canonical initiation factors modulate repeat-associated non-AUG translation.

Green KM, Miller SL, Malik I, Todd PK. Green KM, et al. Hum Mol Genet. 2022 Aug 17;31(15):2521-2534. doi: 10.1093/hmg/ddac021. Hum Mol Genet. 2022. PMID: 35220421 Free PMC article.

9

Mechanistic convergence across initiation sites for RAN translation in fragile X associated tremor ataxia syndrome.

Zhang Y, Glineburg MR, Basrur V, Conlon K, Wright SE, Krans A, Hall DA, Todd PK. Zhang Y, et al. Hum Mol Genet. 2022 Jul 21;31(14):2317-2332. doi: 10.1093/hmg/ddab353. Hum Mol Genet. 2022. PMID: 35137065 Free PMC article.

10

Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance.

Bell HN, Rebernick RJ, Goyert J, Singhal R, Kuljanin M, Kerk SA, Huang W, Das NK, Andren A, Solanki S, Miller SL, Todd PK, Fearon ER, Lyssiotis CA, Gygi SP, Mancias JD, Shah YM. Bell HN, et al. Cancer Cell. 2022 Feb 14;40(2):185-200.e6. doi: 10.1016/j.ccell.2021.12.001. Epub 2021 Dec 23. Cancer Cell. 2022. PMID: 34951957 Free PMC article.

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