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GPR97 triggers inflammatory processes in human neutrophils via a macromolecular complex upstream of PAR2 activation.
Nat Commun. 2022 Oct 27;13(1):6385. doi: 10.1038/s41467-022-34083-1.
Nat Commun. 2022.
PMID: 36302784
Free PMC article.
Activation of Adhesion GPCR EMR2/ADGRE2 Induces Macrophage Differentiation and Inflammatory Responses via Gα16/Akt/MAPK/NF-κB Signaling Pathways.
I KY, Huang YS, Hu CH, Tseng WY, Cheng CH, Stacey M, Gordon S, Chang GW, Lin HH.
I KY, et al.
Front Immunol. 2017 Apr 3;8:373. doi: 10.3389/fimmu.2017.00373. eCollection 2017.
Front Immunol. 2017.
PMID: 28421075
Free PMC article.
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The Adhesion G Protein-Coupled Receptor GPR97/ADGRG3 Is Expressed in Human Granulocytes and Triggers Antimicrobial Effector Functions.
Hsiao CC, Chu TY, Wu CJ, van den Biggelaar M, Pabst C, Hébert J, Kuijpers TW, Scicluna BP, I KY, Chen TC, Liebscher I, Hamann J, Lin HH.
Hsiao CC, et al. Among authors: i ky.
Front Immunol. 2018 Dec 3;9:2830. doi: 10.3389/fimmu.2018.02830. eCollection 2018.
Front Immunol. 2018.
PMID: 30559745
Free PMC article.
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Stimulation of Vibratory Urticaria-Associated Adhesion-GPCR, EMR2/ADGRE2, Triggers the NLRP3 Inflammasome Activation Signal in Human Monocytes.
I KY, Tseng WY, Wang WC, Gordon S, Ng KF, Lin HH.
I KY, et al.
Front Immunol. 2021 Jan 8;11:602016. doi: 10.3389/fimmu.2020.602016. eCollection 2020.
Front Immunol. 2021.
PMID: 33488598
Free PMC article.
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Overexpression of FAM46A, a Non-canonical Poly(A) Polymerase, Promotes Hemin-Induced Hemoglobinization in K562 Cells.
Lin HH, Lo YL, Wang WC, Huang KY, I KY, Chang GW.
Lin HH, et al. Among authors: i ky.
Front Cell Dev Biol. 2020 May 26;8:414. doi: 10.3389/fcell.2020.00414. eCollection 2020.
Front Cell Dev Biol. 2020.
PMID: 32528962
Free PMC article.
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