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Targeted Nanoparticle for Co-delivery of HER2 siRNA and a Taxane to Mirror the Standard Treatment of HER2+ Breast Cancer: Efficacy in Breast Tumor and Brain Metastasis.
Ngamcherdtrakul W, Bejan DS, Cruz-Muñoz W, Reda M, Zaidan HY, Siriwon N, Marshall S, Wang R, Nelson MA, Rehwaldt JPC, Gray JW, Hynynen K, Yantasee W. Ngamcherdtrakul W, et al. Among authors: hynynen k. Small. 2022 Mar;18(11):e2107550. doi: 10.1002/smll.202107550. Epub 2022 Jan 27. Small. 2022. PMID: 35083840 Free PMC article.
MR-guided focused ultrasound enhances delivery of trastuzumab to Her2-positive brain metastases.
Meng Y, Reilly RM, Pezo RC, Trudeau M, Sahgal A, Singnurkar A, Perry J, Myrehaug S, Pople CB, Davidson B, Llinas M, Hyen C, Huang Y, Hamani C, Suppiah S, Hynynen K, Lipsman N. Meng Y, et al. Among authors: hynynen k. Sci Transl Med. 2021 Oct 13;13(615):eabj4011. doi: 10.1126/scitranslmed.abj4011. Epub 2021 Oct 13. Sci Transl Med. 2021. PMID: 34644145
Ultrasound for drug and gene delivery to the brain.
Hynynen K. Hynynen K. Adv Drug Deliv Rev. 2008 Jun 30;60(10):1209-17. doi: 10.1016/j.addr.2008.03.010. Epub 2008 Apr 6. Adv Drug Deliv Rev. 2008. PMID: 18486271 Free PMC article. Review.
490 results