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Multivalent viral particles elicit safe and efficient immunoprotection against Nipah Hendra and Ebola viruses.
Ithinji DG, Buchholz DW, Ezzatpour S, Monreal IA, Cong Y, Sahler J, Bangar AS, Imbiakha B, Upadhye V, Liang J, Ma A, Bradel-Tretheway B, Kaza B, Yeo YY, Choi EJ, Johnston GP, Huzella L, Kollins E, Dixit S, Yu S, Postnikova E, Ortega V, August A, Holbrook MR, Aguilar HC. Ithinji DG, et al. Among authors: huzella l. NPJ Vaccines. 2022 Dec 17;7(1):166. doi: 10.1038/s41541-022-00588-5. NPJ Vaccines. 2022. PMID: 36528644 Free PMC article.
Intratracheal exposure of common marmosets to MERS-CoV Jordan-n3/2012 or MERS-CoV EMC/2012 isolates does not result in lethal disease.
Johnson RF, Via LE, Kumar MR, Cornish JP, Yellayi S, Huzella L, Postnikova E, Oberlander N, Bartos C, Ork BL, Mazur S, Allan C, Holbrook MR, Solomon J, Johnson JC, Pickel J, Hensley LE, Jahrling PB. Johnson RF, et al. Among authors: huzella l. Virology. 2015 Nov;485:422-30. doi: 10.1016/j.virol.2015.07.013. Epub 2015 Sep 3. Virology. 2015. PMID: 26342468 Free PMC article.
Loss in lung volume and changes in the immune response demonstrate disease progression in African green monkeys infected by small-particle aerosol and intratracheal exposure to Nipah virus.
Cong Y, Lentz MR, Lara A, Alexander I, Bartos C, Bohannon JK, Hammoud D, Huzella L, Jahrling PB, Janosko K, Jett C, Kollins E, Lackemeyer M, Mollura D, Ragland D, Rojas O, Solomon J, Xu Z, Munster V, Holbrook MR. Cong Y, et al. Among authors: huzella l. PLoS Negl Trop Dis. 2017 Apr 7;11(4):e0005532. doi: 10.1371/journal.pntd.0005532. eCollection 2017 Apr. PLoS Negl Trop Dis. 2017. PMID: 28388650 Free PMC article.
Aerosol exposure to intermediate size Nipah virus particles induces neurological disease in African green monkeys.
Hammoud DA, Lentz MR, Lara A, Bohannon JK, Feuerstein I, Huzella L, Jahrling PB, Lackemeyer M, Laux J, Rojas O, Sayre P, Solomon J, Cong Y, Munster V, Holbrook MR. Hammoud DA, et al. Among authors: huzella l. PLoS Negl Trop Dis. 2018 Nov 21;12(11):e0006978. doi: 10.1371/journal.pntd.0006978. eCollection 2018 Nov. PLoS Negl Trop Dis. 2018. PMID: 30462637 Free PMC article.
The Human Sodium Iodide Symporter as a Reporter Gene for Studying Middle East Respiratory Syndrome Coronavirus Pathogenesis.
Chefer S, Seidel J, Cockrell AS, Yount B, Solomon J, Hagen KR, Liu DX, Huzella LM, Kumar MR, Postnikova E, Bohannon JK, Lackemeyer MG, Cooper K, Endlich-Frazier A, Sharma H, Thomasson D, Bartos C, Sayre PJ, Sims A, Dyall J, Holbrook MR, Jahrling PB, Baric RS, Johnson RF. Chefer S, et al. mSphere. 2018 Dec 12;3(6):e00540-18. doi: 10.1128/mSphere.00540-18. mSphere. 2018. PMID: 30541777 Free PMC article.
In Vivo Activity of Amodiaquine against Ebola Virus Infection.
DeWald LE, Johnson JC, Gerhardt DM, Torzewski LM, Postnikova E, Honko AN, Janosko K, Huzella L, Dowling WE, Eakin AE, Osborn BL, Gahagen J, Tang L, Green CE, Mirsalis JC, Holbrook MR, Jahrling PB, Dyall J, Hensley LE. DeWald LE, et al. Among authors: huzella l. Sci Rep. 2019 Dec 27;9(1):20199. doi: 10.1038/s41598-019-56481-0. Sci Rep. 2019. PMID: 31882748 Free PMC article.
Expanded Histopathology and Tropism of Ebola Virus in the Rhesus Macaque Model: Potential for Sexual Transmission, Altered Adrenomedullary Hormone Production, and Early Viral Replication in Liver.
Liu DX, Cooper TK, Perry DL, Huzella LM, Hischak AMW, Hart RJ, Isic N, Byrum R, Ragland D, St Claire M, Cooper K, Reeder R, Logue J, Jahrling PB, Holbrook MR, Bennett RS, Hensley LE. Liu DX, et al. Among authors: huzella lm. Am J Pathol. 2022 Jan;192(1):121-129. doi: 10.1016/j.ajpath.2021.09.009. Epub 2021 Oct 6. Am J Pathol. 2022. PMID: 34626576 Free PMC article.
Broadly neutralizing antibodies target the coronavirus fusion peptide.
Dacon C, Tucker C, Peng L, Lee CD, Lin TH, Yuan M, Cong Y, Wang L, Purser L, Williams JK, Pyo CW, Kosik I, Hu Z, Zhao M, Mohan D, Cooper AJR, Peterson M, Skinner J, Dixit S, Kollins E, Huzella L, Perry D, Byrum R, Lembirik S, Drawbaugh D, Eaton B, Zhang Y, Yang ES, Chen M, Leung K, Weinberg RS, Pegu A, Geraghty DE, Davidson E, Douagi I, Moir S, Yewdell JW, Schmaljohn C, Crompton PD, Holbrook MR, Nemazee D, Mascola JR, Wilson IA, Tan J. Dacon C, et al. Among authors: huzella l. Science. 2022 Aug 12;377(6607):728-735. doi: 10.1126/science.abq3773. Epub 2022 Jul 12. Science. 2022. PMID: 35857439 Free PMC article.
39 results