Huwiler KG - Search Results

1

Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of Cellular ATP on Target Engagement.

Vasta JD, Corona CR, Wilkinson J, Zimprich CA, Hartnett JR, Ingold MR, Zimmerman K, Machleidt T, Kirkland TA, Huwiler KG, Ohana RF, Slater M, Otto P, Cong M, Wells CI, Berger BT, Hanke T, Glas C, Ding K, Drewry DH, Huber KVM, Willson TM, Knapp S, Müller S, Meisenheimer PL, Fan F, Wood KV, Robers MB. Vasta JD, et al. Among authors: huwiler kg. Cell Chem Biol. 2018 Feb 15;25(2):206-214.e11. doi: 10.1016/j.chembiol.2017.10.010. Epub 2017 Nov 22. Cell Chem Biol. 2018. PMID: 29174542 Free PMC article.

2

Characterization of serotonin 5-hydroxytryptamine-1A receptor activation using a phospho-extracellular-signal regulated kinase 2 sensor.

Huwiler KG, Machleidt T, Chase L, Hanson B, Robers MB. Huwiler KG, et al. Anal Biochem. 2009 Oct 1;393(1):95-104. doi: 10.1016/j.ab.2009.06.018. Epub 2009 Jun 17. Anal Biochem. 2009. PMID: 19539597

3

A fluorescence anisotropy assay for the muscarinic M1 G-protein-coupled receptor.

Huwiler KG, De Rosier T, Hanson B, Vogel KW. Huwiler KG, et al. Assay Drug Dev Technol. 2010 Jun;8(3):356-66. doi: 10.1089/adt.2009.0257. Assay Drug Dev Technol. 2010. PMID: 20233092

4

Biophysical characterization, including disulfide bond assignments, of the anti-angiogenic type 1 domains of human thrombospondin-1.

Huwiler KG, Vestling MM, Annis DS, Mosher DF. Huwiler KG, et al. Biochemistry. 2002 Dec 3;41(48):14329-39. doi: 10.1021/bi026463u. Biochemistry. 2002. PMID: 12450399

5

Fluorescent cascade and direct assays for characterization of RAF signaling pathway inhibitors.

Kupcho KR, Bruinsma R, Hallis TM, Lasky DA, Somberg RL, Turek-Etienne T, Vogel KW, Huwiler KG. Kupcho KR, et al. Among authors: huwiler kg. Curr Chem Genomics. 2008 Feb 25;1:43-53. doi: 10.2174/1875397300801010043. Curr Chem Genomics. 2008. PMID: 20161827 Free PMC article.

6

Homogenous fluorescent assays for characterizing small-molecule activators of AMP-activated protein kinase (AMPK).

Reichling LJ, Riddle SM, Mei B, Bruinsma R, Goossens TA, Huwiler KG, Maffitt M, Newport AM, Qian XD, Ruttimann-Johnson C, Vogel KW. Reichling LJ, et al. Among authors: huwiler kg. Curr Chem Genomics. 2008 Feb 25;1:34-42. doi: 10.2174/1875397300801010034. Curr Chem Genomics. 2008. PMID: 20161826 Free PMC article.

7

Physical characterization of the procollagen module of human thrombospondin 1 expressed in insect cells.

Misenheimer TM, Huwiler KG, Annis DS, Mosher DF. Misenheimer TM, et al. Among authors: huwiler kg. J Biol Chem. 2000 Dec 29;275(52):40938-45. doi: 10.1074/jbc.M007022200. J Biol Chem. 2000. PMID: 11016937 Free article.

8

Expression of recombinant matrix components using baculoviruses.

Mosher DF, Huwiler KG, Misenheimer TM, Annis DS. Mosher DF, et al. Among authors: huwiler kg. Methods Cell Biol. 2002;69:69-81. doi: 10.1016/s0091-679x(02)69008-9. Methods Cell Biol. 2002. PMID: 12071009 No abstract available.

9

Optimizing the MALDI-TOF-MS observation of peptides containing disulfide bonds.

Huwiler KG, Mosher DF, Vestling MM. Huwiler KG, et al. J Biomol Tech. 2003 Dec;14(4):289-97. J Biomol Tech. 2003. PMID: 14715887 Free PMC article.

10

C-mannosylation and O-fucosylation of the thrombospondin type 1 module.

Hofsteenge J, Huwiler KG, Macek B, Hess D, Lawler J, Mosher DF, Peter-Katalinic J. Hofsteenge J, et al. Among authors: huwiler kg. J Biol Chem. 2001 Mar 2;276(9):6485-98. doi: 10.1074/jbc.M008073200. Epub 2000 Nov 6. J Biol Chem. 2001. PMID: 11067851 Free article.

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