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Comprehensive Fragment Screening of the SARS-CoV-2 Proteome Explores Novel Chemical Space for Drug Development.
Angew Chem Int Ed Engl. 2022 Nov 14;61(46):e202205858. doi: 10.1002/anie.202205858. Epub 2022 Oct 13.
Angew Chem Int Ed Engl. 2022.
PMID: 36115062
Free PMC article.
Structural characterization of the intrinsically disordered domain of Mycobacterium tuberculosis protein tyrosine kinase A.
Niesteruk A, Hutchison M, Sreeramulu S, Jonker HRA, Richter C, Abele R, Bock C, Schwalbe H.
Niesteruk A, et al.
FEBS Lett. 2018 Apr;592(7):1233-1245. doi: 10.1002/1873-3468.13022. Epub 2018 Mar 25.
FEBS Lett. 2018.
PMID: 29494752
Free article.
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1H, 13C, and 15N backbone chemical shift assignments of the apo and the ADP-ribose bound forms of the macrodomain of SARS-CoV-2 non-structural protein 3b.
Cantini F, Banci L, Altincekic N, Bains JK, Dhamotharan K, Fuks C, Fürtig B, Gande SL, Hargittay B, Hengesbach M, Hutchison MT, Korn SM, Kubatova N, Kutz F, Linhard V, Löhr F, Meiser N, Pyper DJ, Qureshi NS, Richter C, Saxena K, Schlundt A, Schwalbe H, Sreeramulu S, Tants JN, Wacker A, Weigand JE, Wöhnert J, Tsika AC, Fourkiotis NK, Spyroulias GA.
Cantini F, et al. Among authors: hutchison mt.
Biomol NMR Assign. 2020 Oct;14(2):339-346. doi: 10.1007/s12104-020-09973-4. Epub 2020 Aug 14.
Biomol NMR Assign. 2020.
PMID: 32803496
Free PMC article.
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1H, 13C, and 15N backbone chemical shift assignments of coronavirus-2 non-structural protein Nsp10.
Kubatova N, Qureshi NS, Altincekic N, Abele R, Bains JK, Ceylan B, Ferner J, Fuks C, Hargittay B, Hutchison MT, de Jesus V, Kutz F, Wirtz Martin MA, Meiser N, Linhard V, Pyper DJ, Trucks S, Fürtig B, Hengesbach M, Löhr F, Richter C, Saxena K, Schlundt A, Schwalbe H, Sreeramulu S, Wacker A, Weigand JE, Wirmer-Bartoschek J, Wöhnert J.
Kubatova N, et al. Among authors: hutchison mt.
Biomol NMR Assign. 2021 Apr;15(1):65-71. doi: 10.1007/s12104-020-09984-1. Epub 2020 Nov 7.
Biomol NMR Assign. 2021.
PMID: 33159807
Free PMC article.
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Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications.
Altincekic N, Korn SM, Qureshi NS, Dujardin M, Ninot-Pedrosa M, Abele R, Abi Saad MJ, Alfano C, Almeida FCL, Alshamleh I, de Amorim GC, Anderson TK, Anobom CD, Anorma C, Bains JK, Bax A, Blackledge M, Blechar J, Böckmann A, Brigandat L, Bula A, Bütikofer M, Camacho-Zarco AR, Carlomagno T, Caruso IP, Ceylan B, Chaikuad A, Chu F, Cole L, Crosby MG, de Jesus V, Dhamotharan K, Felli IC, Ferner J, Fleischmann Y, Fogeron ML, Fourkiotis NK, Fuks C, Fürtig B, Gallo A, Gande SL, Gerez JA, Ghosh D, Gomes-Neto F, Gorbatyuk O, Guseva S, Hacker C, Häfner S, Hao B, Hargittay B, Henzler-Wildman K, Hoch JC, Hohmann KF, Hutchison MT, Jaudzems K, Jović K, Kaderli J, Kalniņš G, Kaņepe I, Kirchdoerfer RN, Kirkpatrick J, Knapp S, Krishnathas R, Kutz F, Zur Lage S, Lambertz R, Lang A, Laurents D, Lecoq L, Linhard V, Löhr F, Malki A, Bessa LM, Martin RW, Matzel T, Maurin D, McNutt SW, Mebus-Antunes NC, Meier BH, Meiser N, Mompeán M, Monaca E, Montserret R, Mariño Perez L, Moser C, Muhle-Goll C, Neves-Martins TC, Ni X, Norton-Baker B, Pierattelli R, Pontoriero L, Pustovalova Y, Ohlenschläger O, Orts J, Da Poian AT, Pyper DJ, Richter C, Riek R, Rienstra CM, Robertson A, Pinheiro AS, Sabbatella R, S…
See abstract for full author list ➔
Altincekic N, et al. Among authors: hutchison mt.
Front Mol Biosci. 2021 May 10;8:653148. doi: 10.3389/fmolb.2021.653148. eCollection 2021.
Front Mol Biosci. 2021.
PMID: 34041264
Free PMC article.
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Modulation of Aβ42 Aggregation Kinetics and Pathway by Low-Molecular-Weight Inhibitors.
Hutchison MT, Bellomo G, Cherepanov A, Stirnal E, Fürtig B, Richter C, Linhard V, Gurewitsch E, Lelli M, Morgner N, Schrader T, Schwalbe H.
Hutchison MT, et al.
Chembiochem. 2023 Apr 3;24(7):e202200760. doi: 10.1002/cbic.202200760. Epub 2023 Mar 2.
Chembiochem. 2023.
PMID: 36652672
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Hydrous mantle transition zone indicated by ringwoodite included within diamond.
Pearson DG, Brenker FE, Nestola F, McNeill J, Nasdala L, Hutchison MT, Matveev S, Mather K, Silversmit G, Schmitz S, Vekemans B, Vincze L.
Pearson DG, et al. Among authors: hutchison mt.
Nature. 2014 Mar 13;507(7491):221-4. doi: 10.1038/nature13080.
Nature. 2014.
PMID: 24622201
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Structure of Staphylococcus aureus adenylosuccinate lyase (PurB) and assessment of its potential as a target for structure-based inhibitor discovery.
Fyfe PK, Dawson A, Hutchison MT, Cameron S, Hunter WN.
Fyfe PK, et al. Among authors: hutchison mt.
Acta Crystallogr D Biol Crystallogr. 2010 Aug;66(Pt 8):881-8. doi: 10.1107/S0907444910020081. Epub 2010 Jul 9.
Acta Crystallogr D Biol Crystallogr. 2010.
PMID: 20693687
Free PMC article.
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