Hutchinson CR - Search Results

1

Iterative type II polyketide synthases, cyclases and ketoreductases exhibit context-dependent behavior in the biosynthesis of linear and angular decapolyketides.

Meurer G, Gerlitz M, Wendt-Pienkowski E, Vining LC, Rohr J, Hutchinson CR. Meurer G, et al. Among authors: hutchinson cr. Chem Biol. 1997 Jun;4(6):433-43. doi: 10.1016/s1074-5521(97)90195-2. Chem Biol. 1997. PMID: 9224566

2

Reconstitution of the iterative type II polyketide synthase for tetracenomycin F2 biosynthesis.

Bao W, Wendt-Pienkowski E, Hutchinson CR. Bao W, et al. Among authors: hutchinson cr. Biochemistry. 1998 Jun 2;37(22):8132-8. doi: 10.1021/bi980466i. Biochemistry. 1998. PMID: 9609708

3

The Streptomyces peucetius dpsC gene determines the choice of starter unit in biosynthesis of the daunorubicin polyketide.

Bao W, Sheldon PJ, Wendt-Pienkowski E, Hutchinson CR. Bao W, et al. Among authors: hutchinson cr. J Bacteriol. 1999 Aug;181(15):4690-5. doi: 10.1128/JB.181.15.4690-4695.1999. J Bacteriol. 1999. PMID: 10419974 Free PMC article.

4

Production of aromatic minimal polyketides by the daunorubicin polyketide synthase genes reveals the incompatibility of the heterologous DpsY and JadI cyclases.

Wohlert SE, Wendt-Pienkowski E, Bao W, Hutchinson CR. Wohlert SE, et al. Among authors: hutchinson cr. J Nat Prod. 2001 Aug;64(8):1077-80. doi: 10.1021/np010067f. J Nat Prod. 2001. PMID: 11520231

5

Nucleotide sequence of the tcmII-tcmIV region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens and evidence that the tcmN gene encodes a multifunctional cyclase-dehydratase-O-methyl transferase.

Summers RG, Wendt-Pienkowski E, Motamedi H, Hutchinson CR. Summers RG, et al. Among authors: hutchinson cr. J Bacteriol. 1992 Mar;174(6):1810-20. doi: 10.1128/jb.174.6.1810-1820.1992. J Bacteriol. 1992. PMID: 1548230 Free PMC article.

6

Functional analysis of putative beta-ketoacyl:acyl carrier protein synthase and acyltransferase active site motifs in a type II polyketide synthase of Streptomyces glaucescens.

Meurer G, Hutchinson CR. Meurer G, et al. Among authors: hutchinson cr. J Bacteriol. 1995 Jan;177(2):477-81. doi: 10.1128/jb.177.2.477-481.1995. J Bacteriol. 1995. PMID: 7814341 Free PMC article.

7

The tcmVI region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens encodes the tetracenomycin F1 monooxygenase, tetracenomycin F2 cyclase, and, most likely, a second cyclase.

Summers RG, Wendt-Pienkowski E, Motamedi H, Hutchinson CR. Summers RG, et al. Among authors: hutchinson cr. J Bacteriol. 1993 Dec;175(23):7571-80. doi: 10.1128/jb.175.23.7571-7580.1993. J Bacteriol. 1993. PMID: 8244926 Free PMC article.

8

A study of iterative type II polyketide synthases, using bacterial genes cloned from soil DNA: a means to access and use genes from uncultured microorganisms.

Seow KT, Meurer G, Gerlitz M, Wendt-Pienkowski E, Hutchinson CR, Davies J. Seow KT, et al. Among authors: hutchinson cr. J Bacteriol. 1997 Dec;179(23):7360-8. doi: 10.1128/jb.179.23.7360-7368.1997. J Bacteriol. 1997. PMID: 9393700 Free PMC article.

9

An acyl-coenzyme A carboxylase encoding gene associated with jadomycin biosynthesis in Streptomyces venezuelae ISP5230.

Han L, Yang K, Kulowski K, Wendt-Pienkowski E, Hutchinson CR, Vining LC. Han L, et al. Among authors: hutchinson cr. Microbiology (Reading). 2000 Apr;146 ( Pt 4):903-910. doi: 10.1099/00221287-146-4-903. Microbiology (Reading). 2000. PMID: 10784049 Free article.

10

Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from Streptomyces griseus.

Wendt-Pienkowski E, Huang Y, Zhang J, Li B, Jiang H, Kwon H, Hutchinson CR, Shen B. Wendt-Pienkowski E, et al. Among authors: hutchinson cr. J Am Chem Soc. 2005 Nov 30;127(47):16442-52. doi: 10.1021/ja054376u. J Am Chem Soc. 2005. PMID: 16305230

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