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Single-cell multi-omics sequencing of human spermatogenesis reveals a DNA demethylation event associated with male meiotic recombination.
Huang Y, Li L, An G, Yang X, Cui M, Song X, Lin J, Zhang X, Yao Z, Wan C, Zhou C, Zhao J, Song K, Ren S, Xia X, Fu X, Lan Y, Hu X, Wang W, Wang M, Zheng Y, Miao K, Bai X, Hutchins AP, Chang G, Gao S, Zhao XY. Huang Y, et al. Among authors: hutchins ap. Nat Cell Biol. 2023 Oct;25(10):1520-1534. doi: 10.1038/s41556-023-01232-7. Epub 2023 Sep 18. Nat Cell Biol. 2023. PMID: 37723297
The chromatin accessibility landscape reveals distinct transcriptional regulation in the induction of human primordial germ cell-like cells from pluripotent stem cells.
Wang X, Veerapandian V, Yang X, Song K, Xu X, Cui M, Yuan W, Huang Y, Xia X, Yao Z, Wan C, Luo F, Song X, Wang X, Zheng Y, Hutchins AP, Jauch R, Liang M, Wang C, Liu Z, Chang G, Zhao XY. Wang X, et al. Among authors: hutchins ap. Stem Cell Reports. 2021 May 11;16(5):1245-1261. doi: 10.1016/j.stemcr.2021.03.032. Epub 2021 Apr 29. Stem Cell Reports. 2021. PMID: 33930315 Free PMC article.
Single-cell multiomics sequencing reveals the reprogramming defects in embryos generated by round spermatid injection.
Wang J, Zhou C, Gao S, Song X, Yang X, Fan J, Ren S, Ma L, Zhao J, Cui M, Song K, Wang M, Li C, Zheng Y, Luo F, Miao K, Bai X, Hutchins AP, Li L, Chang G, Zhao XY. Wang J, et al. Among authors: hutchins ap. Sci Adv. 2022 Aug 12;8(32):eabm3976. doi: 10.1126/sciadv.abm3976. Epub 2022 Aug 10. Sci Adv. 2022. PMID: 35947654 Free PMC article.
The oncogene c-Jun impedes somatic cell reprogramming.
Liu J, Han Q, Peng T, Peng M, Wei B, Li D, Wang X, Yu S, Yang J, Cao S, Huang K, Hutchins AP, Liu H, Kuang J, Zhou Z, Chen J, Wu H, Guo L, Chen Y, Chen Y, Li X, Wu H, Liao B, He W, Song H, Yao H, Pan G, Chen J, Pei D. Liu J, et al. Among authors: hutchins ap. Nat Cell Biol. 2015 Jul;17(7):856-67. doi: 10.1038/ncb3193. Epub 2015 Jun 22. Nat Cell Biol. 2015. PMID: 26098572
Generation and Analysis of GATA2w/eGFP Human ESCs Reveal ITGB3/CD61 as a Reliable Marker for Defining Hemogenic Endothelial Cells during Hematopoiesis.
Huang K, Gao J, Du J, Ma N, Zhu Y, Wu P, Zhang T, Wang W, Li Y, Chen Q, Hutchins AP, Yang Z, Zheng Y, Zhang J, Shan Y, Li X, Liao B, Liu J, Wang J, Liu B, Pan G. Huang K, et al. Among authors: hutchins ap. Stem Cell Reports. 2016 Nov 8;7(5):854-868. doi: 10.1016/j.stemcr.2016.09.008. Epub 2016 Oct 13. Stem Cell Reports. 2016. PMID: 27746115 Free PMC article.
Capturing the interactome of newly transcribed RNA.
Bao X, Guo X, Yin M, Tariq M, Lai Y, Kanwal S, Zhou J, Li N, Lv Y, Pulido-Quetglas C, Wang X, Ji L, Khan MJ, Zhu X, Luo Z, Shao C, Lim DH, Liu X, Li N, Wang W, He M, Liu YL, Ward C, Wang T, Zhang G, Wang D, Yang J, Chen Y, Zhang C, Jauch R, Yang YG, Wang Y, Qin B, Anko ML, Hutchins AP, Sun H, Wang H, Fu XD, Zhang B, Esteban MA. Bao X, et al. Among authors: hutchins ap. Nat Methods. 2018 Mar;15(3):213-220. doi: 10.1038/nmeth.4595. Epub 2018 Feb 12. Nat Methods. 2018. PMID: 29431736 Free PMC article.
NCoR/SMRT co-repressors cooperate with c-MYC to create an epigenetic barrier to somatic cell reprogramming.
Zhuang Q, Li W, Benda C, Huang Z, Ahmed T, Liu P, Guo X, Ibañez DP, Luo Z, Zhang M, Abdul MM, Yang Z, Yang J, Huang Y, Zhang H, Huang D, Zhou J, Zhong X, Zhu X, Fu X, Fan W, Liu Y, Xu Y, Ward C, Khan MJ, Kanwal S, Mirza B, Tortorella MD, Tse HF, Chen J, Qin B, Bao X, Gao S, Hutchins AP, Esteban MA. Zhuang Q, et al. Among authors: hutchins ap. Nat Cell Biol. 2018 Apr;20(4):400-412. doi: 10.1038/s41556-018-0047-x. Epub 2018 Mar 12. Nat Cell Biol. 2018. PMID: 29531310
Publisher Correction: NCoR/SMRT co-repressors cooperate with c-MYC to create an epigenetic barrier to somatic cell reprogramming.
Zhuang Q, Li W, Benda C, Huang Z, Ahmed T, Liu P, Guo X, Ibañez DP, Luo Z, Zhang M, Abdul MM, Yang Z, Yang J, Huang Y, Zhang H, Huang D, Zhou J, Zhong X, Zhu X, Fu X, Fan W, Liu Y, Xu Y, Ward C, Khan MJ, Kanwal S, Mirza B, Tortorella MD, Tse HF, Chen J, Qin B, Bao X, Gao S, Hutchins AP, Esteban MA. Zhuang Q, et al. Among authors: hutchins ap. Nat Cell Biol. 2018 Oct;20(10):1227. doi: 10.1038/s41556-018-0128-x. Nat Cell Biol. 2018. PMID: 29907862
82 results