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Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing.
Replogle JM, Norman TM, Xu A, Hussmann JA, Chen J, Cogan JZ, Meer EJ, Terry JM, Riordan DP, Srinivas N, Fiddes IT, Arthur JG, Alvarado LJ, Pfeiffer KA, Mikkelsen TS, Weissman JS, Adamson B. Replogle JM, et al. Among authors: hussmann ja. Nat Biotechnol. 2020 Aug;38(8):954-961. doi: 10.1038/s41587-020-0470-y. Epub 2020 Mar 30. Nat Biotechnol. 2020. PMID: 32231336 Free PMC article.
The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins.
Shurtleff MJ, Itzhak DN, Hussmann JA, Schirle Oakdale NT, Costa EA, Jonikas M, Weibezahn J, Popova KD, Jan CH, Sinitcyn P, Vembar SS, Hernandez H, Cox J, Burlingame AL, Brodsky JL, Frost A, Borner GH, Weissman JS. Shurtleff MJ, et al. Among authors: hussmann ja. Elife. 2018 May 29;7:e37018. doi: 10.7554/eLife.37018. Elife. 2018. PMID: 29809151 Free PMC article.
Ribosome Profiling: Global Views of Translation.
Ingolia NT, Hussmann JA, Weissman JS. Ingolia NT, et al. Among authors: hussmann ja. Cold Spring Harb Perspect Biol. 2019 May 1;11(5):a032698. doi: 10.1101/cshperspect.a032698. Cold Spring Harb Perspect Biol. 2019. PMID: 30037969 Free PMC article. Review.
Regulation of translation by methylation multiplicity of 18S rRNA.
Liu K, Santos DA, Hussmann JA, Wang Y, Sutter BM, Weissman JS, Tu BP. Liu K, et al. Among authors: hussmann ja. Cell Rep. 2021 Mar 9;34(10):108825. doi: 10.1016/j.celrep.2021.108825. Cell Rep. 2021. PMID: 33691096 Free PMC article.
CRISPR-based functional genomics in human dendritic cells.
Jost M, Jacobson AN, Hussmann JA, Cirolia G, Fischbach MA, Weissman JS. Jost M, et al. Among authors: hussmann ja. Elife. 2021 Apr 27;10:e65856. doi: 10.7554/eLife.65856. Elife. 2021. PMID: 33904395 Free PMC article.
Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning.
Koblan LW, Arbab M, Shen MW, Hussmann JA, Anzalone AV, Doman JL, Newby GA, Yang D, Mok B, Replogle JM, Xu A, Sisley TA, Weissman JS, Adamson B, Liu DR. Koblan LW, et al. Among authors: hussmann ja. Nat Biotechnol. 2021 Nov;39(11):1414-1425. doi: 10.1038/s41587-021-00938-z. Epub 2021 Jun 28. Nat Biotechnol. 2021. PMID: 34183861 Free PMC article.
23 results