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Conjunctival epithelial cells resist productive SARS-CoV-2 infection.
Jackson RM, Hatton CF, Spegarova JS, Georgiou M, Collin J, Stephenson E, Verdon B, Haq IJ, Hussain R, Coxhead JM, Mudhar HS, Wagner B, Hasoon M, Davey T, Rooney P, Khan CMA, Ward C, Brodlie M, Haniffa M, Hambleton S, Armstrong L, Figueiredo F, Queen R, Duncan CJA, Lako M. Jackson RM, et al. Among authors: hussain r. Stem Cell Reports. 2022 Jul 12;17(7):1699-1713. doi: 10.1016/j.stemcr.2022.05.017. Epub 2022 Jun 23. Stem Cell Reports. 2022. PMID: 35750043 Free PMC article.
An induced pluripotent stem cell model of hypoplastic left heart syndrome (HLHS) reveals multiple expression and functional differences in HLHS-derived cardiac myocytes.
Jiang Y, Habibollah S, Tilgner K, Collin J, Barta T, Al-Aama JY, Tesarov L, Hussain R, Trafford AW, Kirkwood G, Sernagor E, Eleftheriou CG, Przyborski S, Stojković M, Lako M, Keavney B, Armstrong L. Jiang Y, et al. Among authors: hussain r. Stem Cells Transl Med. 2014 Apr;3(4):416-23. doi: 10.5966/sctm.2013-0105. Epub 2014 Mar 3. Stem Cells Transl Med. 2014. PMID: 24591732 Free PMC article.
Somatic mtDNA variation is an important component of Parkinson's disease.
Coxhead J, Kurzawa-Akanbi M, Hussain R, Pyle A, Chinnery P, Hudson G. Coxhead J, et al. Among authors: hussain r. Neurobiol Aging. 2016 Feb;38:217.e1-217.e6. doi: 10.1016/j.neurobiolaging.2015.10.036. Epub 2015 Nov 6. Neurobiol Aging. 2016. PMID: 26639157 Free PMC article.
Early-onset autoimmune disease due to a heterozygous loss-of-function mutation in TNFAIP3 (A20).
Duncan CJA, Dinnigan E, Theobald R, Grainger A, Skelton AJ, Hussain R, Willet JDP, Swan DJ, Coxhead J, Thomas MF, Thomas J, Zamvar V, Slatter MA, Cant AJ, Engelhardt KR, Hambleton S. Duncan CJA, et al. Among authors: hussain r. Ann Rheum Dis. 2018 May;77(5):783-786. doi: 10.1136/annrheumdis-2016-210944. Epub 2017 Jun 28. Ann Rheum Dis. 2018. PMID: 28659290 Free PMC article. No abstract available.
Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in STAT2.
Duncan CJA, Thompson BJ, Chen R, Rice GI, Gothe F, Young DF, Lovell SC, Shuttleworth VG, Brocklebank V, Corner B, Skelton AJ, Bondet V, Coxhead J, Duffy D, Fourrage C, Livingston JH, Pavaine J, Cheesman E, Bitetti S, Grainger A, Acres M, Innes BA, Mikulasova A, Sun R, Hussain R, Wright R, Wynn R, Zarhrate M, Zeef LAH, Wood K, Hughes SM, Harris CL, Engelhardt KR, Crow YJ, Randall RE, Kavanagh D, Hambleton S, Briggs TA. Duncan CJA, et al. Among authors: hussain r. Sci Immunol. 2019 Dec 13;4(42):eaav7501. doi: 10.1126/sciimmunol.aav7501. Sci Immunol. 2019. PMID: 31836668 Free PMC article.
Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface.
Collin J, Queen R, Zerti D, Dorgau B, Georgiou M, Djidrovski I, Hussain R, Coxhead JM, Joseph A, Rooney P, Lisgo S, Figueiredo F, Armstrong L, Lako M. Collin J, et al. Among authors: hussain r. Ocul Surf. 2021 Jan;19:190-200. doi: 10.1016/j.jtos.2020.05.013. Epub 2020 Jun 3. Ocul Surf. 2021. PMID: 32502616 Free PMC article.
A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells.
Collin J, Queen R, Zerti D, Bojic S, Dorgau B, Moyse N, Molina MM, Yang C, Dey S, Reynolds G, Hussain R, Coxhead JM, Lisgo S, Henderson D, Joseph A, Rooney P, Ghosh S, Clarke L, Connon C, Haniffa M, Figueiredo F, Armstrong L, Lako M. Collin J, et al. Among authors: hussain r. Ocul Surf. 2021 Jul;21:279-298. doi: 10.1016/j.jtos.2021.03.010. Epub 2021 Apr 16. Ocul Surf. 2021. PMID: 33865984 Free PMC article.
1,327 results