Husain K - Search Results

1

Global Phosphoproteomics Reveal CDK Suppression as a Vulnerability to KRas Addiction in Pancreatic Cancer.

Kazi A, Chen L, Xiang S, Vangipurapu R, Yang H, Beato F, Fang B, Williams TM, Husain K, Underwood P, Fleming JB, Malafa M, Welsh EA, Koomen J, Trevino J, Sebti SM. Kazi A, et al. Among authors: husain k. Clin Cancer Res. 2021 Jul 15;27(14):4012-4024. doi: 10.1158/1078-0432.CCR-20-4781. Epub 2021 Apr 20. Clin Cancer Res. 2021. PMID: 33879459 Free PMC article.

2

Vitamin E δ-tocotrienol augments the antitumor activity of gemcitabine and suppresses constitutive NF-κB activation in pancreatic cancer.

Husain K, Francois RA, Yamauchi T, Perez M, Sebti SM, Malafa MP. Husain K, et al. Mol Cancer Ther. 2011 Dec;10(12):2363-72. doi: 10.1158/1535-7163.MCT-11-0424. Epub 2011 Oct 4. Mol Cancer Ther. 2011. PMID: 21971120 Free PMC article.

3

Prolonged survival and delayed progression of pancreatic intraepithelial neoplasia in LSL-KrasG12D/+;Pdx-1-Cre mice by vitamin E δ-tocotrienol.

Husain K, Centeno BA, Chen DT, Fulp WJ, Perez M, Zhang Lee G, Luetteke N, Hingorani SR, Sebti SM, Malafa MP. Husain K, et al. Carcinogenesis. 2013 Apr;34(4):858-63. doi: 10.1093/carcin/bgt002. Epub 2013 Jan 9. Carcinogenesis. 2013. PMID: 23302291 Free PMC article.

4

Vitamin E δ-tocotrienol prolongs survival in the LSL-KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre (KPC) transgenic mouse model of pancreatic cancer.

Husain K, Centeno BA, Chen DT, Hingorani SR, Sebti SM, Malafa MP. Husain K, et al. Cancer Prev Res (Phila). 2013 Oct;6(10):1074-83. doi: 10.1158/1940-6207.CAPR-13-0157. Epub 2013 Aug 20. Cancer Prev Res (Phila). 2013. PMID: 23963802 Free PMC article.

5

Triciribine Phosphate Monohydrate, an AKT Inhibitor, Enhances Gemcitabine Activity in Pancreatic Cancer Cells.

Kim R, Yamauchi T, Husain K, Sebti S, Malafa M. Kim R, et al. Among authors: husain k. Anticancer Res. 2015 Sep;35(9):4599-604. Anticancer Res. 2015. PMID: 26254348

6

δ-Tocotrienol, a natural form of vitamin E, inhibits pancreatic cancer stem-like cells and prevents pancreatic cancer metastasis.

Husain K, Centeno BA, Coppola D, Trevino J, Sebti SM, Malafa MP. Husain K, et al. Oncotarget. 2017 May 9;8(19):31554-31567. doi: 10.18632/oncotarget.15767. Oncotarget. 2017. PMID: 28404939 Free PMC article.

7

Vitamin E δ-tocotrienol induces p27(Kip1)-dependent cell-cycle arrest in pancreatic cancer cells via an E2F-1-dependent mechanism.

Hodul PJ, Dong Y, Husain K, Pimiento JM, Chen J, Zhang A, Francois R, Pledger WJ, Coppola D, Sebti SM, Chen DT, Malafa MP. Hodul PJ, et al. Among authors: husain k. PLoS One. 2013;8(2):e52526. doi: 10.1371/journal.pone.0052526. Epub 2013 Feb 5. PLoS One. 2013. PMID: 23393547 Free PMC article.

8

MK-2206, an Akt inhibitor, enhances carboplatinum/paclitaxel efficacy in gastric cancer cell lines.

Almhanna K, Cubitt CL, Zhang S, Kazim S, Husain K, Sullivan D, Sebti S, Malafa M. Almhanna K, et al. Among authors: husain k. Cancer Biol Ther. 2013 Oct 1;14(10):932-6. doi: 10.4161/cbt.25939. Epub 2013 Aug 5. Cancer Biol Ther. 2013. PMID: 23917345 Free PMC article.

9

EGR-1/Bax pathway plays a role in vitamin E δ-tocotrienol-induced apoptosis in pancreatic cancer cells.

Wang C, Husain K, Zhang A, Centeno BA, Chen DT, Tong Z, Sebti SM, Malafa MP. Wang C, et al. Among authors: husain k. J Nutr Biochem. 2015 Aug;26(8):797-807. doi: 10.1016/j.jnutbio.2015.02.008. Epub 2015 Apr 1. J Nutr Biochem. 2015. PMID: 25997867 Free PMC article.

10

Vitamin E δ-tocotrienol sensitizes human pancreatic cancer cells to TRAIL-induced apoptosis through proteasome-mediated down-regulation of c-FLIP_s.

Francois RA, Zhang A, Husain K, Wang C, Hutchinson S, Kongnyuy M, Batra SK, Coppola D, Sebti SM, Malafa MP. Francois RA, et al. Among authors: husain k. Cancer Cell Int. 2019 Jul 22;19:189. doi: 10.1186/s12935-019-0876-0. eCollection 2019. Cancer Cell Int. 2019. PMID: 31367187 Free PMC article.

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