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Protein phosphatase 2A activation as a therapeutic strategy for managing MYC-driven cancers.
Farrington CC, Yuan E, Mazhar S, Izadmehr S, Hurst L, Allen-Petersen BL, Janghorban M, Chung E, Wolczanski G, Galsky M, Sears R, Sangodkar J, Narla G. Farrington CC, et al. Among authors: hurst l. J Biol Chem. 2020 Jan 17;295(3):757-770. doi: 10.1074/jbc.RA119.011443. Epub 2019 Dec 10. J Biol Chem. 2020. PMID: 31822503 Free PMC article.
The SRG rat, a Sprague-Dawley Rag2/Il2rg double-knockout validated for human tumor oncology studies.
Noto FK, Sangodkar J, Adedeji BT, Moody S, McClain CB, Tong M, Ostertag E, Crawford J, Gao X, Hurst L, O'Connor CM, Hanson EN, Izadmehr S, Tohmé R, Narla J, LeSueur K, Bhattacharya K, Rupani A, Tayeh MK, Innis JW, Galsky MD, Evers BM, DiFeo A, Narla G, Jamling TY. Noto FK, et al. Among authors: hurst l. PLoS One. 2020 Oct 7;15(10):e0240169. doi: 10.1371/journal.pone.0240169. eCollection 2020. PLoS One. 2020. PMID: 33027304 Free PMC article.
Epistasis, core-genome disharmony, and adaptation in recombining bacteria.
Taylor AJ, Yahara K, Pascoe B, Ko S, Mageiros L, Mourkas E, Calland JK, Puranen S, Hitchings MD, Jolley KA, Kobras CM, Bayliss S, Williams NJ, van Vliet AHM, Parkhill J, Maiden MCJ, Corander J, Hurst LD, Falush D, Keim P, Didelot X, Kelly DJ, Sheppard SK. Taylor AJ, et al. Among authors: hurst ld. mBio. 2024 Apr 29:e0058124. doi: 10.1128/mbio.00581-24. Online ahead of print. mBio. 2024. PMID: 38683013 Free article.
Re-evaluating evidence for adaptive mutation rate variation.
Wang L, Ho AT, Hurst LD, Yang S. Wang L, et al. Among authors: hurst ld. Nature. 2023 Jul;619(7971):E52-E56. doi: 10.1038/s41586-023-06314-y. Epub 2023 Jul 26. Nature. 2023. PMID: 37495884 Free PMC article. No abstract available.
550 results