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Venetoclax enhances T cell-mediated antileukemic activity by increasing ROS production.
Lee JB, Khan DH, Hurren R, Xu M, Na Y, Kang H, Mirali S, Wang X, Gronda M, Jitkova Y, MacLean N, Arruda A, Alaniz Z, Konopleva MY, Andreeff M, Minden MD, Zhang L, Schimmer AD. Lee JB, et al. Among authors: hurren r. Blood. 2021 Jul 22;138(3):234-245. doi: 10.1182/blood.2020009081. Blood. 2021. PMID: 34292323 Free PMC article.
Critical role for Fas-associated death domain-like interleukin-1-converting enzyme-like inhibitory protein in anoikis resistance and distant tumor formation.
Mawji IA, Simpson CD, Hurren R, Gronda M, Williams MA, Filmus J, Jonkman J, Da Costa RS, Wilson BC, Thomas MP, Reed JC, Glinsky GV, Schimmer AD. Mawji IA, et al. Among authors: hurren r. J Natl Cancer Inst. 2007 May 16;99(10):811-22. doi: 10.1093/jnci/djk182. J Natl Cancer Inst. 2007. PMID: 17505076
A chemical biology screen identifies glucocorticoids that regulate c-maf expression by increasing its proteasomal degradation through up-regulation of ubiquitin.
Mao X, Stewart AK, Hurren R, Datti A, Zhu X, Zhu Y, Shi C, Lee K, Tiedemann R, Eberhard Y, Trudel S, Liang S, Corey SJ, Gillis LC, Barber DL, Wrana JL, Ezzat S, Schimmer AD. Mao X, et al. Among authors: hurren r. Blood. 2007 Dec 1;110(12):4047-54. doi: 10.1182/blood-2007-05-088666. Epub 2007 Sep 17. Blood. 2007. PMID: 17875808 Free article.
Cyproheptadine displays preclinical activity in myeloma and leukemia.
Mao X, Liang SB, Hurren R, Gronda M, Chow S, Xu GW, Wang X, Beheshti Zavareh R, Jamal N, Messner H, Hedley DW, Datti A, Wrana JL, Zhu Y, Shi CX, Lee K, Tiedemann R, Trudel S, Stewart AK, Schimmer AD. Mao X, et al. Among authors: hurren r. Blood. 2008 Aug 1;112(3):760-9. doi: 10.1182/blood-2008-02-142687. Epub 2008 May 23. Blood. 2008. PMID: 18502826 Free article.
75 results