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Page 1
Complement lectin pathway activation is associated with COVID-19 disease severity, independent of MBL2 genotype subgroups.
Hurler L, Szilágyi Á, Mescia F, Bergamaschi L, Mező B, Sinkovits G, Réti M, Müller V, Iványi Z, Gál J, Gopcsa L, Reményi P, Szathmáry B, Lakatos B, Szlávik J, Bobek I, Prohászka ZZ, Förhécz Z, Csuka D, Kajdácsi E, Cervenak L, Kiszel P, Masszi T, Vályi-Nagy I, Würzner R; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration; Lyons PA, Toonen EJM, Prohászka Z. Hurler L, et al. Front Immunol. 2023 Mar 27;14:1162171. doi: 10.3389/fimmu.2023.1162171. eCollection 2023. Front Immunol. 2023. PMID: 37051252 Free PMC article.
Complement Overactivation and Consumption Predicts In-Hospital Mortality in SARS-CoV-2 Infection.
Sinkovits G, Mező B, Réti M, Müller V, Iványi Z, Gál J, Gopcsa L, Reményi P, Szathmáry B, Lakatos B, Szlávik J, Bobek I, Prohászka ZZ, Förhécz Z, Csuka D, Hurler L, Kajdácsi E, Cervenak L, Kiszel P, Masszi T, Vályi-Nagy I, Prohászka Z. Sinkovits G, et al. Among authors: hurler l. Front Immunol. 2021 Mar 25;12:663187. doi: 10.3389/fimmu.2021.663187. eCollection 2021. Front Immunol. 2021. PMID: 33841446 Free PMC article. Clinical Trial.
Associations between the von Willebrand Factor-ADAMTS13 Axis, Complement Activation, and COVID-19 Severity and Mortality.
Sinkovits G, Réti M, Müller V, Iványi Z, Gál J, Gopcsa L, Reményi P, Szathmáry B, Lakatos B, Szlávik J, Bobek I, Prohászka ZZ, Förhécz Z, Mező B, Csuka D, Hurler L, Kajdácsi E, Cervenak L, Kiszel P, Masszi T, Vályi-Nagy I, Prohászka Z. Sinkovits G, et al. Among authors: hurler l. Thromb Haemost. 2022 Feb;122(2):240-256. doi: 10.1055/s-0041-1740182. Epub 2022 Jan 21. Thromb Haemost. 2022. PMID: 35062036 Free PMC article.
Complement Levels at Admission Reflecting Progression to Severe Acute Kidney Injury (AKI) in Coronavirus Disease 2019 (COVID-19): A Multicenter Prospective Cohort Study.
Henry BM, Sinkovits G, Szergyuk I, de Oliveira MHS, Lippi G, Benoit JL, Favaloro EJ, Pode-Shakked N, Benoit SW, Cooper DS, Müller V, Iványi Z, Gál J, Réti M, Gopcsa L, Reményi P, Szathmáry B, Lakatos B, Szlávik J, Bobek I, Prohászka ZZ, Förhécz Z, Csuka D, Hurler L, Kajdácsi E, Cervenak L, Mező B, Kiszel P, Masszi T, Vályi-Nagy I, Prohászka Z. Henry BM, et al. Among authors: hurler l. Front Med (Lausanne). 2022 Apr 29;9:796109. doi: 10.3389/fmed.2022.796109. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35572977 Free PMC article.
Evidence, detailed characterization and clinical context of complement activation in acute multisystem inflammatory syndrome in children.
Sinkovits G, Schnur J, Hurler L, Kiszel P, Prohászka ZZ, Sík P, Kajdácsi E, Cervenak L, Maráczi V, Dávid M, Zsigmond B, Rimanóczy É, Bereczki C, Willems L, Toonen EJM, Prohászka Z. Sinkovits G, et al. Among authors: hurler l. Sci Rep. 2022 Nov 17;12(1):19759. doi: 10.1038/s41598-022-23806-5. Sci Rep. 2022. PMID: 36396679 Free PMC article.
Distinction of early complement classical and lectin pathway activation via quantification of C1s/C1-INH and MASP-1/C1-INH complexes using novel ELISAs.
Hurler L, Toonen EJM, Kajdácsi E, van Bree B, Brandwijk RJMGE, de Bruin W, Lyons PA, Bergamaschi L; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration; Sinkovits G, Cervenak L, Würzner R, Prohászka Z. Hurler L, et al. Front Immunol. 2022 Nov 4;13:1039765. doi: 10.3389/fimmu.2022.1039765. eCollection 2022. Front Immunol. 2022. PMID: 36420270 Free PMC article.
Combination protein biomarkers predict multiple sclerosis diagnosis and outcomes.
Kodosaki E, Watkins WJ, Loveless S, Kreft KL, Richards A, Anderson V, Hurler L, Robertson NP, Zelek WM, Tallantyre EC. Kodosaki E, et al. Among authors: hurler l. J Neuroinflammation. 2024 Feb 17;21(1):52. doi: 10.1186/s12974-024-03036-4. J Neuroinflammation. 2024. PMID: 38368354 Free PMC article.
Storage of Transfusion Platelet Concentrates Is Associated with Complement Activation and Reduced Ability of Platelets to Respond to Protease-Activated Receptor-1 and Thromboxane A2 Receptor.
Andersson LI, Sjöström DJ, Quach HQ, Hägerström K, Hurler L, Kajdácsi E, Cervenak L, Prohászka Z, Toonen EJM, Mohlin C, Mollnes TE, Sandgren P, Tjernberg I, Nilsson PH. Andersson LI, et al. Among authors: hurler l. Int J Mol Sci. 2024 Jan 16;25(2):1091. doi: 10.3390/ijms25021091. Int J Mol Sci. 2024. PMID: 38256162 Free PMC article.