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Cigarette smoke extracts induce overexpression of the proto-oncogenic gene interleukin-13 receptor α2 through activation of the PKA-CREB signaling pathway to trigger malignant transformation of lung vascular endothelial cells and angiogenesis.
Meng M, Liao H, Zhang B, Pan Y, Kong Y, Liu W, Yang P, Huo Z, Cao Z, Zhou Q. Meng M, et al. Among authors: huo z. Cell Signal. 2017 Feb;31:15-25. doi: 10.1016/j.cellsig.2016.12.006. Epub 2016 Dec 13. Cell Signal. 2017. PMID: 27986643
The lipogenic LXR-SREBF1 signaling pathway controls cancer cell DNA repair and apoptosis and is a vulnerable point of malignant tumors for cancer therapy.
Yang B, Zhang B, Cao Z, Xu X, Huo Z, Zhang P, Xiang S, Zhao Z, Lv C, Meng M, Zhang G, Dong L, Shi S, Yang L, Zhou Q. Yang B, et al. Among authors: huo z. Cell Death Differ. 2020 Aug;27(8):2433-2450. doi: 10.1038/s41418-020-0514-3. Epub 2020 Mar 6. Cell Death Differ. 2020. PMID: 32144382 Free PMC article.
1,089 results