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PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension.
Cao Y, Zhang X, Wang L, Yang Q, Ma Q, Xu J, Wang J, Kovacs L, Ayon RJ, Liu Z, Zhang M, Zhou Y, Zeng X, Xu Y, Wang Y, Fulton DJ, Weintraub NL, Lucas R, Dong Z, Yuan JX, Sullivan JC, Meadows L, Barman SA, Wu C, Quan J, Hong M, Su Y, Huo Y. Cao Y, et al. Among authors: huo y. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13394-13403. doi: 10.1073/pnas.1821401116. Epub 2019 Jun 18. Proc Natl Acad Sci U S A. 2019. PMID: 31213542 Free PMC article.
Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses.
Huo Y, Guo X, Li H, Xu H, Halim V, Zhang W, Wang H, Fan YY, Ong KT, Woo SL, Chapkin RS, Mashek DG, Chen Y, Dong H, Lu F, Wei L, Wu C. Huo Y, et al. J Biol Chem. 2012 Jun 15;287(25):21492-500. doi: 10.1074/jbc.M112.370379. Epub 2012 May 3. J Biol Chem. 2012. PMID: 22556414 Free PMC article.
Endothelial PFKFB3 plays a critical role in angiogenesis.
Xu Y, An X, Guo X, Habtetsion TG, Wang Y, Xu X, Kandala S, Li Q, Li H, Zhang C, Caldwell RB, Fulton DJ, Su Y, Hoda MN, Zhou G, Wu C, Huo Y. Xu Y, et al. Among authors: huo y. Arterioscler Thromb Vasc Biol. 2014 Jun;34(6):1231-9. doi: 10.1161/ATVBAHA.113.303041. Epub 2014 Apr 3. Arterioscler Thromb Vasc Biol. 2014. PMID: 24700124 Free PMC article.
Tubular p53 regulates multiple genes to mediate AKI.
Zhang D, Liu Y, Wei Q, Huo Y, Liu K, Liu F, Dong Z. Zhang D, et al. Among authors: huo y. J Am Soc Nephrol. 2014 Oct;25(10):2278-89. doi: 10.1681/ASN.2013080902. Epub 2014 Apr 3. J Am Soc Nephrol. 2014. PMID: 24700871 Free PMC article.
3,319 results