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IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development.
Goh W, Sudholz H, Foroutan M, Scheer S, Pfefferle A, Delconte RB, Meng X, Shen Z, Hennessey R, Kong IY, Schuster IS, Andoniou CE, Davis MJ, Hediyeh-Zadeh S, Souza-Fonseca-Guimaraes F, Parish IA, Beavis P, Thiele D, Chopin M, Degli-Esposti MA, Cursons J, Kallies A, Rautela J, Nutt SL, Huntington ND. Goh W, et al. Among authors: huntington nd. Nat Immunol. 2024 Feb;25(2):240-255. doi: 10.1038/s41590-023-01718-4. Epub 2024 Jan 5. Nat Immunol. 2024. PMID: 38182668
Optimisation of a primary human CAR-NK cell manufacturing pipeline.
Pfefferle A, Contet J, Wong K, Chen C, Verhoeyen E, Slichter CK, Schluns KS, Cursons J, Berry R, Nikolic I, Rautela J, Huntington ND. Pfefferle A, et al. Among authors: huntington nd. Clin Transl Immunology. 2024 May 2;13(5):e1507. doi: 10.1002/cti2.1507. eCollection 2024. Clin Transl Immunology. 2024. PMID: 38707997 Free PMC article.
The cancer-natural killer cell immunity cycle.
Huntington ND, Cursons J, Rautela J. Huntington ND, et al. Nat Rev Cancer. 2020 Aug;20(8):437-454. doi: 10.1038/s41568-020-0272-z. Epub 2020 Jun 24. Nat Rev Cancer. 2020. PMID: 32581320 Review.
The Antitumor Effect of Heparin is not Mediated by Direct NK Cell Activation.
Rossi GR, Gonçalves JP, McCulloch T, Delconte RB, Hennessy RJ, Huntington ND, Trindade ES, Souza-Fonseca-Guimaraes F. Rossi GR, et al. Among authors: huntington nd. J Clin Med. 2020 Aug 18;9(8):2666. doi: 10.3390/jcm9082666. J Clin Med. 2020. PMID: 32824699 Free PMC article.
MAIT cells regulate NK cell-mediated tumor immunity.
Petley EV, Koay HF, Henderson MA, Sek K, Todd KL, Keam SP, Lai J, House IG, Li J, Zethoven M, Chen AXY, Oliver AJ, Michie J, Freeman AJ, Giuffrida L, Chan JD, Pizzolla A, Mak JYW, McCulloch TR, Souza-Fonseca-Guimaraes F, Kearney CJ, Millen R, Ramsay RG, Huntington ND, McCluskey J, Oliaro J, Fairlie DP, Neeson PJ, Godfrey DI, Beavis PA, Darcy PK. Petley EV, et al. Among authors: huntington nd. Nat Commun. 2021 Aug 6;12(1):4746. doi: 10.1038/s41467-021-25009-4. Nat Commun. 2021. PMID: 34362900 Free PMC article.
Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity.
Bernard PL, Delconte R, Pastor S, Laletin V, Costa Da Silva C, Goubard A, Josselin E, Castellano R, Krug A, Vernerey J, Devillier R, Olive D, Verhoeyen E, Vivier E, Huntington ND, Nunes J, Guittard G. Bernard PL, et al. Among authors: huntington nd. J Immunother Cancer. 2022 May;10(5):e004244. doi: 10.1136/jitc-2021-004244. J Immunother Cancer. 2022. PMID: 35589278 Free PMC article.
133 results