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Structure of a specialized acyl carrier protein essential for lipid A biosynthesis with very long-chain fatty acids in open and closed conformations.
Ramelot TA, Rossi P, Forouhar F, Lee HW, Yang Y, Ni S, Unser S, Lew S, Seetharaman J, Xiao R, Acton TB, Everett JK, Prestegard JH, Hunt JF, Montelione GT, Kennedy MA. Ramelot TA, et al. Among authors: hunt jf. Biochemistry. 2012 Sep 18;51(37):7239-49. doi: 10.1021/bi300546b. Epub 2012 Sep 7. Biochemistry. 2012. PMID: 22876860 Free PMC article.
Robotic cloning and Protein Production Platform of the Northeast Structural Genomics Consortium.
Acton TB, Gunsalus KC, Xiao R, Ma LC, Aramini J, Baran MC, Chiang YW, Climent T, Cooper B, Denissova NG, Douglas SM, Everett JK, Ho CK, Macapagal D, Rajan PK, Shastry R, Shih LY, Swapna GV, Wilson M, Wu M, Gerstein M, Inouye M, Hunt JF, Montelione GT. Acton TB, et al. Among authors: hunt jf. Methods Enzymol. 2005;394:210-43. doi: 10.1016/S0076-6879(05)94008-1. Methods Enzymol. 2005. PMID: 15808222
Comparisons of NMR spectral quality and success in crystallization demonstrate that NMR and X-ray crystallography are complementary methods for small protein structure determination.
Snyder DA, Chen Y, Denissova NG, Acton T, Aramini JM, Ciano M, Karlin R, Liu J, Manor P, Rajan PA, Rossi P, Swapna GV, Xiao R, Rost B, Hunt J, Montelione GT. Snyder DA, et al. J Am Chem Soc. 2005 Nov 30;127(47):16505-11. doi: 10.1021/ja053564h. J Am Chem Soc. 2005. PMID: 16305237
Crystal structures of two bacterial 3-hydroxy-3-methylglutaryl-CoA lyases suggest a common catalytic mechanism among a family of TIM barrel metalloenzymes cleaving carbon-carbon bonds.
Forouhar F, Hussain M, Farid R, Benach J, Abashidze M, Edstrom WC, Vorobiev SM, Xiao R, Acton TB, Fu Z, Kim JJ, Miziorko HM, Montelione GT, Hunt JF. Forouhar F, et al. Among authors: hunt jf. J Biol Chem. 2006 Mar 17;281(11):7533-45. doi: 10.1074/jbc.M507996200. Epub 2005 Dec 5. J Biol Chem. 2006. PMID: 16330546 Free article.
The structural basis of cyclic diguanylate signal transduction by PilZ domains.
Benach J, Swaminathan SS, Tamayo R, Handelman SK, Folta-Stogniew E, Ramos JE, Forouhar F, Neely H, Seetharaman J, Camilli A, Hunt JF. Benach J, et al. Among authors: hunt jf. EMBO J. 2007 Dec 12;26(24):5153-66. doi: 10.1038/sj.emboj.7601918. Epub 2007 Nov 22. EMBO J. 2007. PMID: 18034161 Free PMC article.
Protein production and purification.
Structural Genomics Consortium; China Structural Genomics Consortium; Northeast Structural Genomics Consortium; Gräslund S, Nordlund P, Weigelt J, Hallberg BM, Bray J, Gileadi O, Knapp S, Oppermann U, Arrowsmith C, Hui R, Ming J, dhe-Paganon S, Park HW, Savchenko A, Yee A, Edwards A, Vincentelli R, Cambillau C, Kim R, Kim SH, Rao Z, Shi Y, Terwilliger TC, Kim CY, Hung LW, Waldo GS, Peleg Y, Albeck S, Unger T, Dym O, Prilusky J, Sussman JL, Stevens RC, Lesley SA, Wilson IA, Joachimiak A, Collart F, Dementieva I, Donnelly MI, Eschenfeldt WH, Kim Y, Stols L, Wu R, Zhou M, Burley SK, Emtage JS, Sauder JM, Thompson D, Bain K, Luz J, Gheyi T, Zhang F, Atwell S, Almo SC, Bonanno JB, Fiser A, Swaminathan S, Studier FW, Chance MR, Sali A, Acton TB, Xiao R, Zhao L, Ma LC, Hunt JF, Tong L, Cunningham K, Inouye M, Anderson S, Janjua H, Shastry R, Ho CK, Wang D, Wang H, Jiang M, Montelione GT, Stuart DI, Owens RJ, Daenke S, Schütz A, Heinemann U, Yokoyama S, Büssow K, Gunsalus KC. Structural Genomics Consortium, et al. Among authors: hunt jf. Nat Methods. 2008 Feb;5(2):135-46. doi: 10.1038/nmeth.f.202. Nat Methods. 2008. PMID: 18235434 Free PMC article. Review.
Structure and dynamics of the P7 protein from the bacteriophage phi 12.
Eryilmaz E, Benach J, Su M, Seetharaman J, Dutta K, Wei H, Gottlieb P, Hunt JF, Ghose R. Eryilmaz E, et al. Among authors: hunt jf. J Mol Biol. 2008 Oct 3;382(2):402-22. doi: 10.1016/j.jmb.2008.07.006. Epub 2008 Jul 11. J Mol Biol. 2008. PMID: 18647606 Free PMC article.
164 results