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The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.
Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium; Swerdlow DI, Holmes MV, Kuchenbaecker KB, Engmann JE, Shah T, Sofat R, Guo Y, Chung C, Peasey A, Pfister R, Mooijaart SP, Ireland HA, Leusink M, Langenberg C, Li KW, Palmen J, Howard P, Cooper JA, Drenos F, Hardy J, Nalls MA, Li YR, Lowe G, Stewart M, Bielinski SJ, Peto J, Timpson NJ, Gallacher J, Dunlop M, Houlston R, Tomlinson I, Tzoulaki I, Luan J, Boer JM, Forouhi NG, Onland-Moret NC, van der Schouw YT, Schnabel RB, Hubacek JA, Kubinova R, Baceviciene M, Tamosiunas A, Pajak A, Topor-Madry R, Malyutina S, Baldassarre D, Sennblad B, Tremoli E, de Faire U, Ferrucci L, Bandenelli S, Tanaka T, Meschia JF, Singleton A, Navis G, Mateo Leach I, Bakker SJ, Gansevoort RT, Ford I, Epstein SE, Burnett MS, Devaney JM, Jukema JW, Westendorp RG, Jan de Borst G, van der Graaf Y, de Jong PA, Mailand-van der Zee AH, Klungel OH, de Boer A, Doevendans PA, Stephens JW, Eaton CB, Robinson JG, Manson JE, Fowkes FG, Frayling TM, Price JF, Whincup PH, Morris RW, Lawlor DA, Smith GD, Ben-Shlomo Y, Redline S, Lange LA, Kumari M, Wareham NJ, Verschuren WM, Benjamin EJ, Whittaker JC, Hamsten A, Dudbridge F, Delaney JA, Wong A, K… See abstract for full author list ➔ Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium, et al. Among authors: humphries se. Lancet. 2012 Mar 31;379(9822):1214-24. doi: 10.1016/S0140-6736(12)60110-X. Epub 2012 Mar 14. Lancet. 2012. PMID: 22421340 Free PMC article.
DNA polymorphisms and the apolipoprotein B gene.
Talmud P, Humphries S. Talmud P, et al. Lancet. 1986 Jul 12;2(8498):104. doi: 10.1016/s0140-6736(86)91635-1. Lancet. 1986. PMID: 2873361 No abstract available.
Peroxisome proliferator-activated receptor alpha gene variants influence progression of coronary atherosclerosis and risk of coronary artery disease.
Flavell DM, Jamshidi Y, Hawe E, Pineda Torra I, Taskinen MR, Frick MH, Nieminen MS, Kesäniemi YA, Pasternack A, Staels B, Miller G, Humphries SE, Talmud PJ, Syvänne M. Flavell DM, et al. Among authors: humphries se. Circulation. 2002 Mar 26;105(12):1440-5. doi: 10.1161/01.cir.0000012145.80593.25. Circulation. 2002. PMID: 11914252
In search of genetic precision.
Humphries SE, Hawe E, Dhamrait S, Miller GJ, Talmud PJ. Humphries SE, et al. Lancet. 2003 May 31;361(9372):1908-9; author reply 1909-10. doi: 10.1016/S0140-6736(03)13516-7. Lancet. 2003. PMID: 12788598 No abstract available.
842 results