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Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants.
Li Q, Humphries F, Girardin RC, Wallace A, Ejemel M, Amcheslavsky A, McMahon CT, Schiller ZA, Ma Z, Cruz J, Dupuis AP, Payne AF, Maryam A, Yilmaz NK, McDonough KA, Pierce BG, Schiffer CA, Kruse AC, Klempner MS, Cavacini LA, Fitzgerald KA, Wang Y. Li Q, et al. Among authors: humphries f. Front Immunol. 2022 Sep 12;13:995412. doi: 10.3389/fimmu.2022.995412. eCollection 2022. Front Immunol. 2022. PMID: 36172366 Free PMC article.
Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade.
Jiang Y, Yang Y, Hu Y, Yang R, Huang J, Liu Y, Wu Y, Li S, Ma C, Humphries F, Wang B, Wang X, Hu Z, Yang S. Jiang Y, et al. Among authors: humphries f. Cell Rep. 2022 Oct 25;41(4):111553. doi: 10.1016/j.celrep.2022.111553. Cell Rep. 2022. PMID: 36288704 Free article.
Assembling the Inflammasome, Piece by Piece.
Humphries F, Fitzgerald KA. Humphries F, et al. J Immunol. 2019 Sep 1;203(5):1093-1094. doi: 10.4049/jimmunol.1900764. J Immunol. 2019. PMID: 31427397 No abstract available.
Loosening the grip on nuclear cGAS.
Humphries F, Fitzgerald KA. Humphries F, et al. Nat Genet. 2020 Dec;52(12):1269-1270. doi: 10.1038/s41588-020-00746-2. Nat Genet. 2020. PMID: 33230301 No abstract available.
CNBP restricts SARS-CoV2 by regulating IFN and disrupting RNA-protein condensates.
Fitzgerald K, Chen Y, Lei X, Jiang Z, Humphries F, Mustone N, Ramos I, Mutetwa T, Fernandez-Sesma A. Fitzgerald K, et al. Among authors: humphries f. Res Sq [Preprint]. 2022 May 2:rs.3.rs-1576788. doi: 10.21203/rs.3.rs-1576788/v1. Res Sq. 2022. PMID: 35547851 Free PMC article. Updated. Preprint.
Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection.
Hariharan VN, Shin M, Chang CW, O'Reilly D, Biscans A, Yamada K, Guo Z, Somasundaran M, Tang Q, Monopoli K, Krishnamurthy PM, Devi G, McHugh N, Cooper DA, Echeverria D, Cruz J, Chan IL, Liu P, Lim SY, McConnell J, Singh SP, Hildebrand S, Sousa J, Davis SM, Kennedy Z, Ferguson C, Godinho BMDC, Thillier Y, Caiazzi J, Ly S, Muhuri M, Kelly K, Humphries F, Cousineau A, Parsi KM, Li Q, Wang Y, Maehr R, Gao G, Korkin D, McDougall WM, Finberg RW, Fitzgerald KA, Wang JP, Watts JK, Khvorova A. Hariharan VN, et al. Among authors: humphries f. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2219523120. doi: 10.1073/pnas.2219523120. Epub 2023 Mar 9. Proc Natl Acad Sci U S A. 2023. PMID: 36893269 Free PMC article.
44 results