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183 results

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Protective potential of the gallbladder in primary sclerosing cholangitis.
Cazzagon N, Gonzalez-Sanchez E, El-Mourabit H, Wendum D, Rainteau D, Humbert L, Corpechot C, Chazouillères O, Arrivé L, Housset C, Lemoinne S. Cazzagon N, et al. Among authors: humbert l. JHEP Rep. 2022 Dec 17;5(4):100649. doi: 10.1016/j.jhepr.2022.100649. eCollection 2023 Apr. JHEP Rep. 2022. PMID: 36923239 Free PMC article.
Defects in gallbladder emptying and bile Acid homeostasis in mice with cystic fibrosis transmembrane conductance regulator deficiencies.
Debray D, Rainteau D, Barbu V, Rouahi M, El Mourabit H, Lerondel S, Rey C, Humbert L, Wendum D, Cottart CH, Dawson P, Chignard N, Housset C. Debray D, et al. Among authors: humbert l. Gastroenterology. 2012 Jun;142(7):1581-91.e6. doi: 10.1053/j.gastro.2012.02.033. Epub 2012 Feb 24. Gastroenterology. 2012. PMID: 22370478 Free PMC article.
A Placebo-Controlled Trial of Bezafibrate in Primary Biliary Cholangitis.
Corpechot C, Chazouillères O, Rousseau A, Le Gruyer A, Habersetzer F, Mathurin P, Goria O, Potier P, Minello A, Silvain C, Abergel A, Debette-Gratien M, Larrey D, Roux O, Bronowicki JP, Boursier J, de Ledinghen V, Heurgue-Berlot A, Nguyen-Khac E, Zoulim F, Ollivier-Hourmand I, Zarski JP, Nkontchou G, Lemoinne S, Humbert L, Rainteau D, Lefèvre G, de Chaisemartin L, Chollet-Martin S, Gaouar F, Admane FH, Simon T, Poupon R. Corpechot C, et al. Among authors: humbert l. N Engl J Med. 2018 Jun 7;378(23):2171-2181. doi: 10.1056/NEJMoa1714519. N Engl J Med. 2018. PMID: 29874528 Free article. Clinical Trial.
TGR5 controls bile acid composition and gallbladder function to protect the liver from bile acid overload.
Bidault-Jourdainne V, Merlen G, Glénisson M, Doignon I, Garcin I, Péan N, Boisgard R, Ursic-Bedoya J, Serino M, Ullmer C, Humbert L, Abdelrafee A, Golse N, Vibert E, Duclos-Vallée JC, Rainteau D, Tordjmann T. Bidault-Jourdainne V, et al. Among authors: humbert l. JHEP Rep. 2020 Nov 11;3(2):100214. doi: 10.1016/j.jhepr.2020.100214. eCollection 2021 Apr. JHEP Rep. 2020. PMID: 33604531 Free PMC article.
Bile acid-receptor TGR5 deficiency worsens liver injury in alcohol-fed mice by inducing intestinal microbiota dysbiosis.
Spatz M, Ciocan D, Merlen G, Rainteau D, Humbert L, Gomes-Rochette N, Hugot C, Trainel N, Mercier-Nomé F, Domenichini S, Puchois V, Wrzosek L, Ferrere G, Tordjmann T, Perlemuter G, Cassard AM. Spatz M, et al. Among authors: humbert l. JHEP Rep. 2021 Jan 19;3(2):100230. doi: 10.1016/j.jhepr.2021.100230. eCollection 2021 Apr. JHEP Rep. 2021. PMID: 33665587 Free PMC article.
The Bile Acid Receptor TGR5 and Liver Regeneration.
Jourdainne V, Péan N, Doignon I, Humbert L, Rainteau D, Tordjmann T. Jourdainne V, et al. Among authors: humbert l. Dig Dis. 2015;33(3):319-26. doi: 10.1159/000371668. Epub 2015 May 27. Dig Dis. 2015. PMID: 26045264
Hepatoprotective impact of the bile acid receptor TGR5.
Merlen G, Bidault-Jourdainne V, Kahale N, Glenisson M, Ursic-Bedoya J, Doignon I, Garcin I, Humbert L, Rainteau D, Tordjmann T. Merlen G, et al. Among authors: humbert l. Liver Int. 2020 May;40(5):1005-1015. doi: 10.1111/liv.14427. Epub 2020 Mar 30. Liver Int. 2020. PMID: 32145703
Immediate neuroendocrine signaling after partial hepatectomy through acute portal hyperpressure and cholestasis.
Doignon I, Julien B, Serrière-Lanneau V, Garcin I, Alonso G, Nicou A, Monnet F, Gigou M, Humbert L, Rainteau D, Azoulay D, Castaing D, Gillon MC, Samuel D, Duclos-Vallée JC, Tordjmann T. Doignon I, et al. Among authors: humbert l. J Hepatol. 2011 Mar;54(3):481-8. doi: 10.1016/j.jhep.2010.07.012. Epub 2010 Sep 22. J Hepatol. 2011. PMID: 21163545
183 results