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Advances in Understanding of the Immune Response to Mycobacterial Pathogens and Vaccines through Use of Cattle and Mycobacterium avium subsp. paratuberculosis as a Prototypic Mycobacterial Pathogen.
Davis WC, Abdellrazeq GS, Mahmoud AH, Park KT, Elnaggar MM, Donofrio G, Hulubei V, Fry LM. Davis WC, et al. Among authors: hulubei v. Vaccines (Basel). 2021 Sep 26;9(10):1085. doi: 10.3390/vaccines9101085. Vaccines (Basel). 2021. PMID: 34696193 Free PMC article. Review.
Characterization of leukocyte subsets in buffalo (Bubalus bubalis) with cross-reactive monoclonal antibodies specific for bovine MHC class I and class II molecules and leukocyte differentiation molecules.
Grandoni F, Elnaggar MM, Abdellrazeq GS, Signorelli F, Fry LM, Marchitelli C, Hulubei V, Khaliel SA, Torky HA, Davis WC. Grandoni F, et al. Among authors: hulubei v. Dev Comp Immunol. 2017 Sep;74:101-109. doi: 10.1016/j.dci.2017.04.013. Epub 2017 Apr 20. Dev Comp Immunol. 2017. PMID: 28433527
Identification of monoclonal antibodies cross-reactive with bottlenose dolphin orthologues of the major histocompatibility complex and leukocyte differentiation molecules.
Elnaggar MM, Abdellrazeq GS, Venn-Watson SK, Jensen ED, Hulubei V, Fry LM, Sacco RE, Davis WC. Elnaggar MM, et al. Among authors: hulubei v. Vet Immunol Immunopathol. 2017 Oct;192:54-59. doi: 10.1016/j.vetimm.2017.09.007. Epub 2017 Oct 3. Vet Immunol Immunopathol. 2017. PMID: 29042015
A Mycobacterium avium subsp. paratuberculosis relA deletion mutant and a 35 kDa major membrane protein elicit development of cytotoxic T lymphocytes with ability to kill intracellular bacteria.
Abdellrazeq GS, Elnaggar MM, Bannantine JP, Park KT, Souza CD, Backer B, Hulubei V, Fry LM, Khaliel SA, Torky HA, Schneider DA, Davis WC. Abdellrazeq GS, et al. Among authors: hulubei v. Vet Res. 2018 Jun 26;49(1):53. doi: 10.1186/s13567-018-0549-3. Vet Res. 2018. PMID: 29941017 Free PMC article.
A peptide-based vaccine for Mycobacterium avium subspecies paratuberculosis.
Abdellrazeq GS, Elnaggar MM, Bannantine JP, Schneider DA, Souza CD, Hwang J, Mahmoud AHA, Hulubei V, Fry LM, Park KT, Davis WC. Abdellrazeq GS, et al. Among authors: hulubei v. Vaccine. 2019 May 9;37(21):2783-2790. doi: 10.1016/j.vaccine.2019.04.040. Epub 2019 Apr 16. Vaccine. 2019. PMID: 31003915
Simultaneous cognate epitope recognition by bovine CD4 and CD8 T cells is essential for primary expansion of antigen-specific cytotoxic T-cells following ex vivo stimulation with a candidate Mycobacterium avium subsp. paratuberculosis peptide vaccine.
Abdellrazeq GS, Fry LM, Elnaggar MM, Bannantine JP, Schneider DA, Chamberlin WM, Mahmoud AHA, Park KT, Hulubei V, Davis WC. Abdellrazeq GS, et al. Among authors: hulubei v. Vaccine. 2020 Feb 18;38(8):2016-2025. doi: 10.1016/j.vaccine.2019.12.052. Epub 2020 Jan 3. Vaccine. 2020. PMID: 31902643
Capacity to Elicit Cytotoxic CD8 T Cell Activity Against Mycobacterium avium subsp. paratuberculosis Is Retained in a Vaccine Candidate 35 kDa Peptide Modified for Expression in Mammalian Cells.
Franceschi V, Mahmoud AH, Abdellrazeq GS, Tebaldi G, Macchi F, Russo L, Fry LM, Elnaggar MM, Bannantine JP, Park KT, Hulubei V, Cavirani S, Davis WC, Donofrio G. Franceschi V, et al. Among authors: hulubei v. Front Immunol. 2019 Dec 11;10:2859. doi: 10.3389/fimmu.2019.02859. eCollection 2019. Front Immunol. 2019. PMID: 31921129 Free PMC article.
relA is Achilles' heel for mycobacterial pathogens as demonstrated with deletion mutants in Mycobacterium avium subsp. paratuberculosis and mycobacterium bovis bacillus Calmette-Guérin (BCG).
Abdellrazeq GS, Mahmoud AH, Park KT, Fry LM, Elnaggar MM, Schneider DA, Hulubei V, Davis WC. Abdellrazeq GS, et al. Among authors: hulubei v. Tuberculosis (Edinb). 2020 Jan;120:101904. doi: 10.1016/j.tube.2020.101904. Epub 2020 Jan 15. Tuberculosis (Edinb). 2020. PMID: 32090858
16 results