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An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor.
Reyes Gaido OE, Pavlaki N, Granger JM, Mesubi OO, Liu B, Lin BL, Long A, Walker D, Mayourian J, Schole KL, Terrillion CE, Nkashama LJ, Hulsurkar MM, Dorn LE, Ferrero KM, Huganir RL, Müller FU, Wehrens XHT, Liu JO, Luczak ED, Bezzerides VJ, Anderson ME. Reyes Gaido OE, et al. Among authors: hulsurkar mm. Sci Transl Med. 2023 Jun 21;15(701):eabq7839. doi: 10.1126/scitranslmed.abq7839. Epub 2023 Jun 21. Sci Transl Med. 2023. PMID: 37343080 Free PMC article.
Atrial-Specific Gene Delivery Using an Adeno-Associated Viral Vector.
Ni L, Scott L Jr, Campbell HM, Pan X, Alsina KM, Reynolds J, Philippen LE, Hulsurkar M, Lagor WR, Li N, Wehrens XHT. Ni L, et al. Circ Res. 2019 Jan 18;124(2):256-262. doi: 10.1161/CIRCRESAHA.118.313811. Circ Res. 2019. PMID: 30582449 Free PMC article.
Loss of SPEG Inhibitory Phosphorylation of Ryanodine Receptor Type-2 Promotes Atrial Fibrillation.
Campbell HM, Quick AP, Abu-Taha I, Chiang DY, Kramm CF, Word TA, Brandenburg S, Hulsurkar M, Alsina KM, Liu HB, Martin B, Uhlenkamp D, Moore OM, Lahiri SK, Corradini E, Kamler M, Heck AJR, Lehnart SE, Dobrev D, Wehrens XHT. Campbell HM, et al. Circulation. 2020 Sep 22;142(12):1159-1172. doi: 10.1161/CIRCULATIONAHA.120.045791. Epub 2020 Jul 20. Circulation. 2020. PMID: 32683896 Free PMC article.
Mouse models of spontaneous atrial fibrillation.
Keefe JA, Hulsurkar MM, Reilly S, Wehrens XHT. Keefe JA, et al. Among authors: hulsurkar mm. Mamm Genome. 2023 Jun;34(2):298-311. doi: 10.1007/s00335-022-09964-x. Epub 2022 Sep 29. Mamm Genome. 2023. PMID: 36173465 Free PMC article. Review.
Kinase Inhibitors and Atrial Fibrillation: Mechanisms of Action and Clinical Implications.
Potter AS, Hulsurkar MM, Wu L, Narasimhan B, Karimzad K, Koutroumpakis E, Palaskas N, Deswal A, Kantharia BK, Wehrens XHT. Potter AS, et al. Among authors: hulsurkar mm. JACC Clin Electrophysiol. 2023 Apr;9(4):591-602. doi: 10.1016/j.jacep.2022.11.034. Epub 2023 Feb 22. JACC Clin Electrophysiol. 2023. PMID: 37100538 Free article. Review.
17 results