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201 results

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Dietary methionine starvation impairs acute myeloid leukemia progression.
Cunningham A, Erdem A, Alshamleh I, Geugien M, Pruis M, Pereira-Martins DA, van den Heuvel FAJ, Wierenga ATJ, Ten Berge H, Dennebos R, van den Boom V, Hogeling SM, Weinhäuser I, Knops R, de Blaauw P, Heiner-Fokkema MR, Woolthuis C, Günther UL, Rego EM, Martens JHA, Jansen JH, Schwalbe H, Huls G, Schuringa JJ. Cunningham A, et al. Among authors: huls g. Blood. 2022 Nov 10;140(19):2037-2052. doi: 10.1182/blood.2022017575. Blood. 2022. PMID: 35984907 Free article.
The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia.
Erdem A, Marin S, Pereira-Martins DA, Cortés R, Cunningham A, Pruis MG, de Boer B, van den Heuvel FAJ, Geugien M, Wierenga ATJ, Brouwers-Vos AZ, Rego EM, Huls G, Cascante M, Schuringa JJ. Erdem A, et al. Among authors: huls g. Nat Commun. 2022 Mar 1;13(1):1105. doi: 10.1038/s41467-022-28737-3. Nat Commun. 2022. PMID: 35232995 Free PMC article.
Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability.
Erdem A, Marin S, Pereira-Martins DA, Geugien M, Cunningham A, Pruis MG, Weinhäuser I, Gerding A, Bakker BM, Wierenga ATJ, Rego EM, Huls G, Cascante M, Schuringa JJ. Erdem A, et al. Among authors: huls g. Nat Commun. 2022 Apr 19;13(1):2013. doi: 10.1038/s41467-022-29639-0. Nat Commun. 2022. PMID: 35440568 Free PMC article.
Monocytosis and its association with clonal hematopoiesis in community-dwelling individuals.
van Zeventer IA, de Graaf AO, Koorenhof-Scheele TN, van der Reijden BA, van der Klauw MM, Dinmohamed AG, Diepstra A, Schuringa JJ, Malcovati L, Huls G, Jansen JH. van Zeventer IA, et al. Among authors: huls g. Blood Adv. 2022 Jul 26;6(14):4174-4184. doi: 10.1182/bloodadvances.2021006755. Blood Adv. 2022. PMID: 35561316 Free PMC article.
201 results