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Symptomatic androgen deficiency develops only when both total and free testosterone decline in obese men who may have incident biochemical secondary hypogonadism: Prospective results from the EMAS.
Rastrelli G, O'Neill TW, Ahern T, Bártfai G, Casanueva FF, Forti G, Keevil B, Giwercman A, Han TS, Slowikowska-Hilczer J, Lean MEJ, Pendleton N, Punab M, Antonio L, Tournoy J, Vanderschueren D, Maggi M, Huhtaniemi IT, Wu FCW; EMAS study group. Rastrelli G, et al. Among authors: huhtaniemi it. Clin Endocrinol (Oxf). 2018 Oct;89(4):459-469. doi: 10.1111/cen.13756. Epub 2018 Jul 23. Clin Endocrinol (Oxf). 2018. PMID: 29855071
Erectile dysfunction predicts mortality in middle-aged and older men independent of their sex steroid status.
Antonio L, Wu FCW, Moors H, Matheï C, Huhtaniemi IT, Rastrelli G, Dejaeger M, O'Neill TW, Pye SR, Forti G, Maggi M, Casanueva FF, Slowikowska-Hilczer J, Punab M, Tournoy J, Vanderschueren D; EMAS Study Group. Antonio L, et al. Among authors: huhtaniemi it. Age Ageing. 2022 Apr 1;51(4):afac094. doi: 10.1093/ageing/afac094. Age Ageing. 2022. PMID: 35429269
Reproductive hormone levels, androgen receptor CAG repeat length and their longitudinal relationships with decline in cognitive subdomains in men: The European Male Ageing Study.
Overman MJ, Pendleton N, O'Neill TW, Bartfai G, Casanueva FF, Forti G, Rastrelli G, Giwercman A, Han TS, Huhtaniemi IT, Slowikowska-Hilczer J, Lean ME, Punab M, Lee DM, Antonio L, Gielen E, Rutter MK, Vanderschueren D, Wu FC, Tournoy J. Overman MJ, et al. Among authors: huhtaniemi it. Physiol Behav. 2022 Aug 1;252:113825. doi: 10.1016/j.physbeh.2022.113825. Epub 2022 Apr 26. Physiol Behav. 2022. PMID: 35487276
Association of age, hormonal, and lifestyle factors with the Leydig cell biomarker INSL3 in aging men from the European Male Aging Study cohort.
Anand-Ivell R, Heng K, Severn K, Antonio L, Bartfai G, Casanueva FF, Huhtaniemi IT, Giwercman A, Maggi M, O'Neill TW, Punab M, Rastrelli G, Slowikowska-Hilczer J, Tournoy J, Vanderschueren D, Wu FCW, Ivell R. Anand-Ivell R, et al. Among authors: huhtaniemi it. Andrology. 2022 Oct;10(7):1328-1338. doi: 10.1111/andr.13220. Epub 2022 Jul 11. Andrology. 2022. PMID: 35770372 Free PMC article.
Hypothalamic-pituitary-testicular axis disruptions in older men are differentially linked to age and modifiable risk factors: the European Male Aging Study.
Wu FC, Tajar A, Pye SR, Silman AJ, Finn JD, O'Neill TW, Bartfai G, Casanueva F, Forti G, Giwercman A, Huhtaniemi IT, Kula K, Punab M, Boonen S, Vanderschueren D; European Male Aging Study Group. Wu FC, et al. Among authors: huhtaniemi it. J Clin Endocrinol Metab. 2008 Jul;93(7):2737-45. doi: 10.1210/jc.2007-1972. Epub 2008 Feb 12. J Clin Endocrinol Metab. 2008. PMID: 18270261
Increased estrogen rather than decreased androgen action is associated with longer androgen receptor CAG repeats.
Huhtaniemi IT, Pye SR, Limer KL, Thomson W, O'Neill TW, Platt H, Payne D, John SL, Jiang M, Boonen S, Borghs H, Vanderschueren D, Adams JE, Ward KA, Bartfai G, Casanueva F, Finn JD, Forti G, Giwercman A, Han TS, Kula K, Lean ME, Pendleton N, Punab M, Silman AJ, Wu FC; European Male Ageing Study Group. Huhtaniemi IT, et al. J Clin Endocrinol Metab. 2009 Jan;94(1):277-84. doi: 10.1210/jc.2008-0848. Epub 2008 Oct 7. J Clin Endocrinol Metab. 2009. PMID: 18840639 Free article.
Effect of polymorphisms in selected genes involved in pituitary-testicular function on reproductive hormones and phenotype in aging men.
Huhtaniemi IT, Pye SR, Holliday KL, Thomson W, O'Neill TW, Platt H, Payne D, John SL, Jiang M, Bartfai G, Boonen S, Casanueva FF, Finn JD, Forti G, Giwercman A, Han TS, Kula K, Lean ME, Pendleton N, Punab M, Silman AJ, Vanderschueren D, Labrie F, Wu FC; European Male Aging Study Group. Huhtaniemi IT, et al. J Clin Endocrinol Metab. 2010 Apr;95(4):1898-908. doi: 10.1210/jc.2009-2071. Epub 2010 Feb 19. J Clin Endocrinol Metab. 2010. PMID: 20173016 Free article.
Characteristics of secondary, primary, and compensated hypogonadism in aging men: evidence from the European Male Ageing Study.
Tajar A, Forti G, O'Neill TW, Lee DM, Silman AJ, Finn JD, Bartfai G, Boonen S, Casanueva FF, Giwercman A, Han TS, Kula K, Labrie F, Lean ME, Pendleton N, Punab M, Vanderschueren D, Huhtaniemi IT, Wu FC; EMAS Group. Tajar A, et al. Among authors: huhtaniemi it. J Clin Endocrinol Metab. 2010 Apr;95(4):1810-8. doi: 10.1210/jc.2009-1796. Epub 2010 Feb 19. J Clin Endocrinol Metab. 2010. PMID: 20173018
Endogenous hormones, androgen receptor CAG repeat length and fluid cognition in middle-aged and older men: results from the European Male Ageing Study.
Lee DM, Ulubaev A, Tajar A, Pye SR, Pendleton N, Purandare N, O'Neill TW, O'Connor DB, Labrie F, Platt H, Payne D, Bartfai G, Boonen S, Casanueva FF, Finn JD, Forti G, Giwercman A, Han TS, Huhtaniemi IT, Kula K, Lean ME, Punab M, Silman AJ, Vanderschueren D, Wu FC; EMAS study group. Lee DM, et al. Among authors: huhtaniemi it. Eur J Endocrinol. 2010 Jun;162(6):1155-64. doi: 10.1530/EJE-09-0970. Epub 2010 Mar 15. Eur J Endocrinol. 2010. PMID: 20231367
504 results