Hughes TA - Search Results

1

Liver x receptor alpha drives chemoresistance in response to side-chain hydroxycholesterols in triple negative breast cancer.

Hutchinson SA, Websdale A, Cioccoloni G, Røberg-Larsen H, Lianto P, Kim B, Rose A, Soteriou C, Pramanik A, Wastall LM, Williams BJ, Henn MA, Chen JJ, Ma L, Moore JB, Nelson E, Hughes TA, Thorne JL. Hutchinson SA, et al. Among authors: hughes ta. Oncogene. 2021 Apr;40(16):2872-2883. doi: 10.1038/s41388-021-01720-w. Epub 2021 Mar 19. Oncogene. 2021. PMID: 33742124 Free PMC article.

2

Neoadjuvant chemotherapy induces expression levels of breast cancer resistance protein that predict disease-free survival in breast cancer.

Kim B, Fatayer H, Hanby AM, Horgan K, Perry SL, Valleley EM, Verghese ET, Williams BJ, Thorne JL, Hughes TA. Kim B, et al. Among authors: hughes ta. PLoS One. 2013 May 2;8(5):e62766. doi: 10.1371/journal.pone.0062766. Print 2013. PLoS One. 2013. PMID: 23658771 Free PMC article.

3

MiR-26b is down-regulated in carcinoma-associated fibroblasts from ER-positive breast cancers leading to enhanced cell migration and invasion.

Verghese ET, Drury R, Green CA, Holliday DL, Lu X, Nash C, Speirs V, Thorne JL, Thygesen HH, Zougman A, Hull MA, Hanby AM, Hughes TA. Verghese ET, et al. Among authors: hughes ta. J Pathol. 2013 Nov;231(3):388-99. doi: 10.1002/path.4248. J Pathol. 2013. PMID: 23939832 Free PMC article.

4

Chemotherapy induces Notch1-dependent MRP1 up-regulation, inhibition of which sensitizes breast cancer cells to chemotherapy.

Kim B, Stephen SL, Hanby AM, Horgan K, Perry SL, Richardson J, Roundhill EA, Valleley EM, Verghese ET, Williams BJ, Thorne JL, Hughes TA. Kim B, et al. Among authors: hughes ta. BMC Cancer. 2015 Sep 11;15:634. doi: 10.1186/s12885-015-1625-y. BMC Cancer. 2015. PMID: 26362310 Free PMC article.

5

CIP2A expression predicts recurrences of tamoxifen-treated breast cancer.

Baldacchino S, Wastall LM, Saliba C, Hughes TA, Scerri C, Berwick A, Speirs V, Hanby AM, Grech G. Baldacchino S, et al. Among authors: hughes ta. Tumour Biol. 2017 Oct;39(10):1010428317722064. doi: 10.1177/1010428317722064. Tumour Biol. 2017. PMID: 29034804 Free article.

6

Neoadjuvant Endocrine Therapy in Breast Cancer Upregulates the Cytotoxic Drug Pump ABCG2/BCRP, and May Lead to Resistance to Subsequent Chemotherapy.

Baxter DE, Kim B, Hanby AM, Verghese ET, Sims AH, Hughes TA. Baxter DE, et al. Among authors: hughes ta. Clin Breast Cancer. 2018 Dec;18(6):481-488. doi: 10.1016/j.clbc.2018.07.002. Epub 2018 Jul 6. Clin Breast Cancer. 2018. PMID: 30055962 Free article.

7

MiR-19b non-canonical binding is directed by HuR and confers chemosensitivity through regulation of P-glycoprotein in breast cancer.

Thorne JL, Battaglia S, Baxter DE, Hayes JL, Hutchinson SA, Jana S, Millican-Slater RA, Smith L, Teske MC, Wastall LM, Hughes TA. Thorne JL, et al. Among authors: hughes ta. Biochim Biophys Acta Gene Regul Mech. 2018 Nov;1861(11):996-1006. doi: 10.1016/j.bbagrm.2018.08.005. Epub 2018 Aug 31. Biochim Biophys Acta Gene Regul Mech. 2018. PMID: 30343695

8

Phytosterols Inhibit Side-Chain Oxysterol Mediated Activation of LXR in Breast Cancer Cells.

Hutchinson SA, Lianto P, Moore JB, Hughes TA, Thorne JL. Hutchinson SA, et al. Among authors: hughes ta. Int J Mol Sci. 2019 Jul 2;20(13):3241. doi: 10.3390/ijms20133241. Int J Mol Sci. 2019. PMID: 31269628 Free PMC article.

9

MicroRNA-222 reprogrammed cancer-associated fibroblasts enhance growth and metastasis of breast cancer.

Chatterjee A, Jana S, Chatterjee S, Wastall LM, Mandal G, Nargis N, Roy H, Hughes TA, Bhattacharyya A. Chatterjee A, et al. Among authors: hughes ta. Br J Cancer. 2019 Oct;121(8):679-689. doi: 10.1038/s41416-019-0566-7. Epub 2019 Sep 4. Br J Cancer. 2019. PMID: 31481734 Free PMC article.

10

ER-Negative Breast Cancer Is Highly Responsive to Cholesterol Metabolite Signalling.

Hutchinson SA, Lianto P, Roberg-Larsen H, Battaglia S, Hughes TA, Thorne JL. Hutchinson SA, et al. Among authors: hughes ta. Nutrients. 2019 Nov 1;11(11):2618. doi: 10.3390/nu11112618. Nutrients. 2019. PMID: 31683867 Free PMC article.

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