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Computer-based Engineering of Thermostabilized Antibody Fragments.
Lee J, Der BS, Karamitros CS, Li W, Marshall NM, Lungu OI, Miklos AE, Xu J, Kang TH, Lee CH, Tan B, Hughes RA, Jung ST, Ippolito GC, Gray JJ, Zhang Y, Kuhlman B, Georgiou G, Ellington AD. Lee J, et al. Among authors: hughes ra. AIChE J. 2020 Mar;66(3):e16864. doi: 10.1002/aic.16864. Epub 2019 Nov 19. AIChE J. 2020. PMID: 32336757 Free PMC article.
Structure-based design of supercharged, highly thermoresistant antibodies.
Miklos AE, Kluwe C, Der BS, Pai S, Sircar A, Hughes RA, Berrondo M, Xu J, Codrea V, Buckley PE, Calm AM, Welsh HS, Warner CR, Zacharko MA, Carney JP, Gray JJ, Georgiou G, Kuhlman B, Ellington AD. Miklos AE, et al. Among authors: hughes ra. Chem Biol. 2012 Apr 20;19(4):449-55. doi: 10.1016/j.chembiol.2012.01.018. Chem Biol. 2012. PMID: 22520751 Free PMC article.
Mistakes in translation don't translate into termination.
Hughes RA, Ellington AD. Hughes RA, et al. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1273-4. doi: 10.1073/pnas.0409443101. Epub 2005 Jan 26. Proc Natl Acad Sci U S A. 2005. PMID: 15677335 Free PMC article. No abstract available.
Gene synthesis: methods and applications.
Hughes RA, Miklos AE, Ellington AD. Hughes RA, et al. Methods Enzymol. 2011;498:277-309. doi: 10.1016/B978-0-12-385120-8.00012-7. Methods Enzymol. 2011. PMID: 21601682
Design and assembly of large synthetic DNA constructs.
Miklos AE, Hughes RA, Ellington AD. Miklos AE, et al. Among authors: hughes ra. Curr Protoc Mol Biol. 2012 Jul;Chapter 3:Unit3.23. doi: 10.1002/0471142727.mb0323s99. Curr Protoc Mol Biol. 2012. PMID: 22870858
665 results