Hughes JR - Search Results

1

Absolute Quantification of Transcription Factors Reveals Principles of Gene Regulation in Erythropoiesis.

Gillespie MA, Palii CG, Sanchez-Taltavull D, Shannon P, Longabaugh WJR, Downes DJ, Sivaraman K, Espinoza HM, Hughes JR, Price ND, Perkins TJ, Ranish JA, Brand M. Gillespie MA, et al. Among authors: hughes jr. Mol Cell. 2020 Jun 4;78(5):960-974.e11. doi: 10.1016/j.molcel.2020.03.031. Epub 2020 Apr 23. Mol Cell. 2020. PMID: 32330456 Free PMC article.

2

Association between active genes occurs at nuclear speckles and is modulated by chromatin environment.

Brown JM, Green J, das Neves RP, Wallace HA, Smith AJ, Hughes J, Gray N, Taylor S, Wood WG, Higgs DR, Iborra FJ, Buckle VJ. Brown JM, et al. J Cell Biol. 2008 Sep 22;182(6):1083-97. doi: 10.1083/jcb.200803174. J Cell Biol. 2008. PMID: 18809724 Free PMC article.

3

Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells.

Kassouf MT, Hughes JR, Taylor S, McGowan SJ, Soneji S, Green AL, Vyas P, Porcher C. Kassouf MT, et al. Among authors: hughes jr. Genome Res. 2010 Aug;20(8):1064-83. doi: 10.1101/gr.104935.110. Epub 2010 Jun 21. Genome Res. 2010. PMID: 20566737 Free PMC article.

4

Intragenic enhancers act as alternative promoters.

Kowalczyk MS, Hughes JR, Garrick D, Lynch MD, Sharpe JA, Sloane-Stanley JA, McGowan SJ, De Gobbi M, Hosseini M, Vernimmen D, Brown JM, Gray NE, Collavin L, Gibbons RJ, Flint J, Taylor S, Buckle VJ, Milne TA, Wood WG, Higgs DR. Kowalczyk MS, et al. Among authors: hughes jr. Mol Cell. 2012 Feb 24;45(4):447-58. doi: 10.1016/j.molcel.2011.12.021. Epub 2012 Jan 19. Mol Cell. 2012. PMID: 22264824 Free article.

5

Analysis of sequence variation underlying tissue-specific transcription factor binding and gene expression.

Lower KM, De Gobbi M, Hughes JR, Derry CJ, Ayyub H, Sloane-Stanley JA, Vernimmen D, Garrick D, Gibbons RJ, Higgs DR. Lower KM, et al. Among authors: hughes jr. Hum Mutat. 2013 Aug;34(8):1140-8. doi: 10.1002/humu.22343. Epub 2013 Jun 18. Hum Mutat. 2013. PMID: 23616472 Free article.

6

Unlinking an lncRNA from Its Associated cis Element.

Paralkar VR, Taborda CC, Huang P, Yao Y, Kossenkov AV, Prasad R, Luan J, Davies JO, Hughes JR, Hardison RC, Blobel GA, Weiss MJ. Paralkar VR, et al. Among authors: hughes jr. Mol Cell. 2016 Apr 7;62(1):104-10. doi: 10.1016/j.molcel.2016.02.029. Epub 2016 Mar 31. Mol Cell. 2016. PMID: 27041223 Free PMC article.

7

Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo.

Simon CS, Downes DJ, Gosden ME, Telenius J, Higgs DR, Hughes JR, Costello I, Bikoff EK, Robertson EJ. Simon CS, et al. Among authors: hughes jr. Development. 2017 Apr 1;144(7):1249-1260. doi: 10.1242/dev.147322. Epub 2017 Feb 7. Development. 2017. PMID: 28174238 Free PMC article.

8

Tissue-specific CTCF-cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo.

Hanssen LLP, Kassouf MT, Oudelaar AM, Biggs D, Preece C, Downes DJ, Gosden M, Sharpe JA, Sloane-Stanley JA, Hughes JR, Davies B, Higgs DR. Hanssen LLP, et al. Among authors: hughes jr. Nat Cell Biol. 2017 Aug;19(8):952-961. doi: 10.1038/ncb3573. Epub 2017 Jul 24. Nat Cell Biol. 2017. PMID: 28737770 Free PMC article.

9

Robust detection of chromosomal interactions from small numbers of cells using low-input Capture-C.

Oudelaar AM, Davies JOJ, Downes DJ, Higgs DR, Hughes JR. Oudelaar AM, et al. Among authors: hughes jr. Nucleic Acids Res. 2017 Dec 15;45(22):e184. doi: 10.1093/nar/gkx1194. Nucleic Acids Res. 2017. PMID: 29186505 Free PMC article.

10

Low-input Capture-C: A Chromosome Conformation Capture Assay to Analyze Chromatin Architecture in Small Numbers of Cells.

Oudelaar AM, Downes DJ, Davies JOJ, Hughes JR. Oudelaar AM, et al. Among authors: hughes jr. Bio Protoc. 2017 Dec 5;7(23):e2645. doi: 10.21769/BioProtoc.2645. Bio Protoc. 2017. PMID: 29270442 Free PMC article.

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