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Clinical and analytical validation of FoundationOne Liquid CDx, a novel 324-Gene cfDNA-based comprehensive genomic profiling assay for cancers of solid tumor origin.
Woodhouse R, Li M, Hughes J, Delfosse D, Skoletsky J, Ma P, Meng W, Dewal N, Milbury C, Clark T, Donahue A, Stover D, Kennedy M, Dacpano-Komansky J, Burns C, Vietz C, Alexander B, Hegde P, Dennis L. Woodhouse R, et al. Among authors: hughes j. PLoS One. 2020 Sep 25;15(9):e0237802. doi: 10.1371/journal.pone.0237802. eCollection 2020. PLoS One. 2020. PMID: 32976510 Free PMC article.
Analytical Validation of a Hybrid Capture-Based Next-Generation Sequencing Clinical Assay for Genomic Profiling of Cell-Free Circulating Tumor DNA.
Clark TA, Chung JH, Kennedy M, Hughes JD, Chennagiri N, Lieber DS, Fendler B, Young L, Zhao M, Coyne M, Breese V, Young G, Donahue A, Pavlick D, Tsiros A, Brennan T, Zhong S, Mughal T, Bailey M, He J, Roels S, Frampton GM, Spoerke JM, Gendreau S, Lackner M, Schleifman E, Peters E, Ross JS, Ali SM, Miller VA, Gregg JP, Stephens PJ, Welsh A, Otto GA, Lipson D. Clark TA, et al. Among authors: hughes jd. J Mol Diagn. 2018 Sep;20(5):686-702. doi: 10.1016/j.jmoldx.2018.05.004. Epub 2018 Jun 22. J Mol Diagn. 2018. PMID: 29936259 Free PMC article.
Driver Mutation Variant Allele Frequency in Circulating Tumor DNA and Association with Clinical Outcome in Patients with Non-Small Cell Lung Cancer and EGFR- and KRAS-Mutated Tumors.
Li M, Yang L, Hughes J, van den Hout A, Burns C, Woodhouse R, Dennis L, Hegde P, Oxnard GR, Vietz C. Li M, et al. Among authors: hughes j. J Mol Diagn. 2022 May;24(5):543-553. doi: 10.1016/j.jmoldx.2022.02.002. Epub 2022 Mar 14. J Mol Diagn. 2022. PMID: 35301118 Free article.
Pan-Cancer Analysis of Copy-Number Features Identifies Recurrent Signatures and a Homologous Recombination Deficiency Biomarker to Predict Poly (ADP-Ribose) Polymerase Inhibitor Response.
Moore JA, Chen KT, Madison R, Newberg JY, Fleischmann Z, Wang S, Sharaf R, Murugesan K, Fendler BJ, Hughes J, Schrock AB, Hegde PS, Oxnard GR, Fabrizio D, Frampton GM, Antonarakis ES, Sokol ES, Jin DX. Moore JA, et al. Among authors: hughes j. JCO Precis Oncol. 2023 Sep;7:e2300093. doi: 10.1200/PO.23.00093. JCO Precis Oncol. 2023. PMID: 37769224
Genomic profiling of cell-free circulating tumor DNA in patients with colorectal cancer and its fidelity to the genomics of the tumor biopsy.
Li G, Pavlick D, Chung JH, Bauer T, Tan BA, Peguero J, Ward P, Kallab A, Bufill J, Hoffman A, Sadiq A, Edenfield J, He J, Cooke M, Hughes J, Forcier B, Nahas M, Stephens P, Ali SM, Schrock AB, Ross JS, Miller VA, Gregg JP. Li G, et al. Among authors: hughes j. J Gastrointest Oncol. 2019 Oct;10(5):831-840. doi: 10.21037/jgo.2019.05.05. J Gastrointest Oncol. 2019. PMID: 31602320 Free PMC article.
Epidemiology and Management Trends of Neuro-Oncology in Nigeria: A Systematic Review and Pooled Analysis.
Ukachukwu AK, Seas A, Oboh EC, Paradie E, Oyemolade TA, Nwaribe EE, Nischal SA, Hughes JG, Ogundeji OD, Badejo OA, Malomo TA, Okere OE, Abu-Bonsrah N, Still MEH, Waguia-Kouam R, Trillo-Ordonez Y, Asemota I, Oboh EN, Rahman R, Reddy P, Ugorji C, von Isenburg M, Fuller AT, Haglund MM, Adeleye AO. Ukachukwu AK, et al. Among authors: hughes jg. World Neurosurg. 2024 May;185:e185-e208. doi: 10.1016/j.wneu.2023.11.071. World Neurosurg. 2024. PMID: 38741325
6,943 results