Hughes CC - Search Results

1

Nitrosopyridine Probe To Detect Polyketide Natural Products with Conjugated Alkenes: Discovery of Novodaryamide and Nocarditriene.

Castro-Falcón G, Millán-Aguiñaga N, Roullier C, Jensen PR, Hughes CC. Castro-Falcón G, et al. Among authors: hughes cc. ACS Chem Biol. 2018 Nov 16;13(11):3097-3106. doi: 10.1021/acschembio.8b00598. Epub 2018 Oct 26. ACS Chem Biol. 2018. PMID: 30272441

2

The marinopyrroles, antibiotics of an unprecedented structure class from a marine Streptomyces sp.

Hughes CC, Prieto-Davo A, Jensen PR, Fenical W. Hughes CC, et al. Org Lett. 2008 Feb 21;10(4):629-31. doi: 10.1021/ol702952n. Epub 2008 Jan 19. Org Lett. 2008. PMID: 18205372 Free PMC article.

3

The ammosamides: structures of cell cycle modulators from a marine-derived Streptomyces species.

Hughes CC, MacMillan JB, Gaudêncio SP, Jensen PR, Fenical W. Hughes CC, et al. Angew Chem Int Ed Engl. 2009;48(4):725-7. doi: 10.1002/anie.200804890. Angew Chem Int Ed Engl. 2009. PMID: 19090514 Free PMC article. No abstract available.

4

Total synthesis of the ammosamides.

Hughes CC, Fenical W. Hughes CC, et al. J Am Chem Soc. 2010 Mar 3;132(8):2528-9. doi: 10.1021/ja9106572. J Am Chem Soc. 2010. PMID: 20131899 Free PMC article.

5

Structures, reactivities, and antibiotic properties of the marinopyrroles A-F.

Hughes CC, Kauffman CA, Jensen PR, Fenical W. Hughes CC, et al. J Org Chem. 2010 May 21;75(10):3240-50. doi: 10.1021/jo1002054. J Org Chem. 2010. PMID: 20405892 Free PMC article.

6

Pharmacological properties of the marine natural product marinopyrrole A against methicillin-resistant Staphylococcus aureus.

Haste NM, Hughes CC, Tran DN, Fenical W, Jensen PR, Nizet V, Hensler ME. Haste NM, et al. Among authors: hughes cc. Antimicrob Agents Chemother. 2011 Jul;55(7):3305-12. doi: 10.1128/AAC.01211-10. Epub 2011 Apr 18. Antimicrob Agents Chemother. 2011. PMID: 21502631 Free PMC article.

7

Chlorizidine, a cytotoxic 5H-pyrrolo[2,1-a]isoindol-5-one-containing alkaloid from a marine Streptomyces sp.

Alvarez-Mico X, Jensen PR, Fenical W, Hughes CC. Alvarez-Mico X, et al. Among authors: hughes cc. Org Lett. 2013 Mar 1;15(5):988-91. doi: 10.1021/ol303374e. Epub 2013 Feb 13. Org Lett. 2013. PMID: 23405849 Free PMC article.

8

Thiol Probes To Detect Electrophilic Natural Products Based on Their Mechanism of Action.

Castro-Falcón G, Hahn D, Reimer D, Hughes CC. Castro-Falcón G, et al. Among authors: hughes cc. ACS Chem Biol. 2016 Aug 19;11(8):2328-36. doi: 10.1021/acschembio.5b00924. Epub 2016 Jun 28. ACS Chem Biol. 2016. PMID: 27294329 Free PMC article.

9

Thiol-Based Probe for Electrophilic Natural Products Reveals That Most of the Ammosamides Are Artifacts.

Reimer D, Hughes CC. Reimer D, et al. Among authors: hughes cc. J Nat Prod. 2017 Jan 27;80(1):126-133. doi: 10.1021/acs.jnatprod.6b00773. Epub 2017 Jan 5. J Nat Prod. 2017. PMID: 28055208

10

Ecological implications of hypoxia-triggered shifts in secondary metabolism.

Gallagher KA, Wanger G, Henderson J, Llorente M, Hughes CC, Jensen PR. Gallagher KA, et al. Among authors: hughes cc. Environ Microbiol. 2017 Jun;19(6):2182-2191. doi: 10.1111/1462-2920.13700. Epub 2017 Mar 21. Environ Microbiol. 2017. PMID: 28205416 Free PMC article.

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