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Methods to Manipulate and Monitor Wnt Signaling in Human Pluripotent Stem Cells.
Methods Mol Biol. 2016;1481:161-81. doi: 10.1007/978-1-4939-6393-5_16.
Methods Mol Biol. 2016.
PMID: 27590161
The WNT receptor FZD7 is required for maintenance of the pluripotent state in human embryonic stem cells.
Fernandez A, Huggins IJ, Perna L, Brafman D, Lu D, Yao S, Gaasterland T, Carson DA, Willert K.
Fernandez A, et al. Among authors: huggins ij.
Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1409-14. doi: 10.1073/pnas.1323697111. Epub 2014 Jan 13.
Proc Natl Acad Sci U S A. 2014.
PMID: 24474766
Free PMC article.
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The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells.
Huggins IJ, Bos T, Gaylord O, Jessen C, Lonquich B, Puranen A, Richter J, Rossdam C, Brafman D, Gaasterland T, Willert K.
Huggins IJ, et al.
Nat Commun. 2017 Oct 18;8(1):1034. doi: 10.1038/s41467-017-01203-1.
Nat Commun. 2017.
PMID: 29044119
Free PMC article.
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Site Selective Antibody-Oligonucleotide Conjugation via Microbial Transglutaminase.
Huggins IJ, Medina CA, Springer AD, van den Berg A, Jadhav S, Cui X, Dowdy SF.
Huggins IJ, et al.
Molecules. 2019 Sep 10;24(18):3287. doi: 10.3390/molecules24183287.
Molecules. 2019.
PMID: 31509944
Free PMC article.
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Insights into innate immune activation via PS-ASO-protein-TLR9 interactions.
Pollak AJ, Zhao L, Vickers TA, Huggins IJ, Liang XH, Crooke ST.
Pollak AJ, et al. Among authors: huggins ij.
Nucleic Acids Res. 2022 Aug 12;50(14):8107-8126. doi: 10.1093/nar/gkac618.
Nucleic Acids Res. 2022.
PMID: 35848907
Free PMC article.
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DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45.
Rai K, Huggins IJ, James SR, Karpf AR, Jones DA, Cairns BR.
Rai K, et al. Among authors: huggins ij.
Cell. 2008 Dec 26;135(7):1201-12. doi: 10.1016/j.cell.2008.11.042.
Cell. 2008.
PMID: 19109892
Free PMC article.
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