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Inactivation of TNF signaling by rationally designed dominant-negative TNF variants.
Steed PM, Tansey MG, Zalevsky J, Zhukovsky EA, Desjarlais JR, Szymkowski DE, Abbott C, Carmichael D, Chan C, Cherry L, Cheung P, Chirino AJ, Chung HH, Doberstein SK, Eivazi A, Filikov AV, Gao SX, Hubert RS, Hwang M, Hyun L, Kashi S, Kim A, Kim E, Kung J, Martinez SP, Muchhal US, Nguyen DH, O'Brien C, O'Keefe D, Singer K, Vafa O, Vielmetter J, Yoder SC, Dahiyat BI. Steed PM, et al. Among authors: hubert rs. Science. 2003 Sep 26;301(5641):1895-8. doi: 10.1126/science.1081297. Science. 2003. PMID: 14512626
The TNF superfamily is on the TRAIL to BlyS.
Steed PM, Hubert RS. Steed PM, et al. Among authors: hubert rs. Drug Discov Today. 2003 Feb 1;8(3):114-7. doi: 10.1016/s1359-6446(02)02592-8. Drug Discov Today. 2003. PMID: 12568780
Modulation of Macropinocytosis-Mediated Internalization Decreases Ocular Toxicity of Antibody-Drug Conjugates.
Zhao H, Atkinson J, Gulesserian S, Zeng Z, Nater J, Ou J, Yang P, Morrison K, Coleman J, Malik F, Challita-Eid P, Karki S, Aviña H, Hubert R, Capo L, Snyder J, Moon SJ, Luethy R, Mendelsohn BA, Stover DR, Doñate F. Zhao H, et al. Cancer Res. 2018 Apr 15;78(8):2115-2126. doi: 10.1158/0008-5472.CAN-17-3202. Epub 2018 Jan 30. Cancer Res. 2018. PMID: 29382707
15 results