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Page 1
Decoding Heterogenous Single-cell Perturbation Responses.
Song B, Liu D, Dai W, McMyn N, Wang Q, Yang D, Krejci A, Vasilyev A, Untermoser N, Loregger A, Song D, Williams B, Rosen B, Cheng X, Chao L, Kale HT, Zhang H, Diao Y, Bürckstümmer T, Siliciano JM, Li JJ, Siliciano R, Huangfu D, Li W. Song B, et al. Among authors: huangfu d. bioRxiv [Preprint]. 2023 Nov 29:2023.10.30.564796. doi: 10.1101/2023.10.30.564796. bioRxiv. 2023. PMID: 37961332 Free PMC article. Preprint.
ChromaFold predicts the 3D contact map from single-cell chromatin accessibility.
Gao VR, Yang R, Das A, Luo R, Luo H, McNally DR, Karagiannidis I, Rivas MA, Wang ZM, Barisic D, Karbalayghareh A, Wong W, Zhan YA, Chin CR, Noble W, Bilmes JA, Apostolou E, Kharas MG, Béguelin W, Viny AD, Huangfu D, Rudensky AY, Melnick AM, Leslie CS. Gao VR, et al. Among authors: huangfu d. bioRxiv [Preprint]. 2023 Jul 28:2023.07.27.550836. doi: 10.1101/2023.07.27.550836. bioRxiv. 2023. PMID: 37546906 Free PMC article. Preprint.
Dynamic network-guided CRISPRi screen identifies CTCF-loop-constrained nonlinear enhancer gene regulatory activity during cell state transitions.
Luo R, Yan J, Oh JW, Xi W, Shigaki D, Wong W, Cho HS, Murphy D, Cutler R, Rosen BP, Pulecio J, Yang D, Glenn RA, Chen T, Li QV, Vierbuchen T, Sidoli S, Apostolou E, Huangfu D, Beer MA. Luo R, et al. Among authors: huangfu d. Nat Genet. 2023 Aug;55(8):1336-1346. doi: 10.1038/s41588-023-01450-7. Epub 2023 Jul 24. Nat Genet. 2023. PMID: 37488417 Free PMC article.
Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project.
Dekker J, Alber F, Aufmkolk S, Beliveau BJ, Bruneau BG, Belmont AS, Bintu L, Boettiger A, Calandrelli R, Disteche CM, Gilbert DM, Gregor T, Hansen AS, Huang B, Huangfu D, Kalhor R, Leslie CS, Li W, Li Y, Ma J, Noble WS, Park PJ, Phillips-Cremins JE, Pollard KS, Rafelski SM, Ren B, Ruan Y, Shav-Tal Y, Shen Y, Shendure J, Shu X, Strambio-De-Castillia C, Vertii A, Zhang H, Zhong S. Dekker J, et al. Among authors: huangfu d. Mol Cell. 2023 Aug 3;83(15):2624-2640. doi: 10.1016/j.molcel.2023.06.018. Epub 2023 Jul 6. Mol Cell. 2023. PMID: 37419111 Review.
Discovery of Competent Chromatin Regions in Human Embryonic Stem Cells.
Pulecio J, Tayyebi Z, Liu D, Wong W, Luo R, Damodaran JR, Kaplan S, Cho H, Yan J, Murphy D, Rickert RW, Shukla A, Zhong A, González F, Yang D, Li W, Zhou T, Apostolou E, Leslie CS, Huangfu D. Pulecio J, et al. Among authors: huangfu d. bioRxiv [Preprint]. 2023 Jun 14:2023.06.14.544990. doi: 10.1101/2023.06.14.544990. bioRxiv. 2023. PMID: 37398096 Free PMC article. Preprint.
Parallel genome-scale CRISPR screens distinguish pluripotency and self-renewal.
Rosen BP, Li QV, Cho H, Liu D, Yang D, Graff S, Yan J, Luo R, Verma N, Damodaran JR, Beer MA, Sidoli S, Huangfu D. Rosen BP, et al. Among authors: huangfu d. bioRxiv [Preprint]. 2023 May 3:2023.05.03.539283. doi: 10.1101/2023.05.03.539283. bioRxiv. 2023. PMID: 37205540 Free PMC article. Preprint.
Dynamic network-guided CRISPRi screen reveals CTCF loop-constrained nonlinear enhancer-gene regulatory activity in cell state transitions.
Luo R, Yan J, Oh JW, Xi W, Shigaki D, Wong W, Cho H, Murphy D, Cutler R, Rosen BP, Pulecio J, Yang D, Glenn R, Chen T, Li QV, Vierbuchen T, Sidoli S, Apostolou E, Huangfu D, Beer MA. Luo R, et al. Among authors: huangfu d. bioRxiv [Preprint]. 2023 Mar 9:2023.03.07.531569. doi: 10.1101/2023.03.07.531569. bioRxiv. 2023. PMID: 36945628 Free PMC article. Updated. Preprint.
Genetic Engineering of Immune Evasive Stem Cell-Derived Islets.
Sackett SD, Kaplan SJ, Mitchell SA, Brown ME, Burrack AL, Grey S, Huangfu D, Odorico J. Sackett SD, et al. Among authors: huangfu d. Transpl Int. 2022 Dec 5;35:10817. doi: 10.3389/ti.2022.10817. eCollection 2022. Transpl Int. 2022. PMID: 36545154 Free PMC article. Review.
84 results