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Epigenetic Alterations of Repeated Relapses in Patient-matched Childhood Ependymomas.
Zhao S, Li J, Zhang H, Qi L, Du Y, Kogiso M, Braun FK, Xiao S, Huang Y, Li J, Teo WY, Lindsay H, Baxter P, Su JMF, Adesina A, Laczik M, Genevini P, Veillard AC, Schvartzman S, Berguet G, Ding SR, Du L, Stephan C, Yang J, Davies PJA, Lu X, Chintagumpala M, Parsons DW, Perlaky L, Xia YF, Man TK, Huang Y, Sun D, Li XN. Zhao S, et al. Among authors: huang y. Nat Commun. 2022 Nov 5;13(1):6689. doi: 10.1038/s41467-022-34514-z. Nat Commun. 2022. PMID: 36335125 Free PMC article.
A patient tumor-derived orthotopic xenograft mouse model replicating the group 3 supratentorial primitive neuroectodermal tumor in children.
Liu Z, Zhao X, Wang Y, Mao H, Huang Y, Kogiso M, Qi L, Baxter PA, Man TK, Adesina A, Su JM, Picard D, Ching Ho K, Huang A, Perlaky L, Lau CC, Chintagumpala M, Li XN. Liu Z, et al. Among authors: huang a, huang y. Neuro Oncol. 2014 Jun;16(6):787-99. doi: 10.1093/neuonc/not244. Epub 2014 Jan 26. Neuro Oncol. 2014. PMID: 24470556 Free PMC article.
Silencing BMI1 eliminates tumor formation of pediatric glioma CD133+ cells not by affecting known targets but by down-regulating a novel set of core genes.
Baxter PA, Lin Q, Mao H, Kogiso M, Zhao X, Liu Z, Huang Y, Voicu H, Gurusiddappa S, Su JM, Adesina AM, Perlaky L, Dauser RC, Leung HC, Muraszko KM, Heth JA, Fan X, Lau CC, Man TK, Chintagumpala M, Li XN. Baxter PA, et al. Among authors: huang y. Acta Neuropathol Commun. 2014 Dec 20;2:160. doi: 10.1186/s40478-014-0160-4. Acta Neuropathol Commun. 2014. PMID: 25526772 Free PMC article.
Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.
Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily MA, Quist MJ, Davis LE, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung TB, Sun W, Kogiso M, Du Y, Qi L, Huang Y, Hütt-Cabezas M, Warren KE, Le Dret L, Meltzer PS, Mao H, Quezado M, van Vuurden DG, Abraham J, Fouladi M, Svalina MN, Wang N, Hawkins C, Nazarian J, Alonso MM, Raabe EH, Hulleman E, Spellman PT, Li XN, Keller C, Pal R, Grill J, Monje M. Grasso CS, et al. Among authors: huang ec, huang y. Nat Med. 2015 Jun;21(6):555-9. doi: 10.1038/nm.3855. Epub 2015 May 4. Nat Med. 2015. PMID: 25939062 Free PMC article.
Preservation of KIT genotype in a novel pair of patient-derived orthotopic xenograft mouse models of metastatic pediatric CNS germinoma.
Lindsay H, Huang Y, Du Y, Braun FK, Teo WY, Kogiso M, Qi L, Zhang H, Zhao S, Mao H, Lin F, Baxter P, Su JM, Terashima K, Perlaky L, Chintagumpala M, Adesina A, Lau CC, Williams Parsons D, Li XN. Lindsay H, et al. Among authors: huang y. J Neurooncol. 2016 May;128(1):47-56. doi: 10.1007/s11060-016-2098-9. Epub 2016 Mar 8. J Neurooncol. 2016. PMID: 26956263 Free PMC article.
Xenotransplantation of pediatric low grade gliomas confirms the enrichment of BRAF V600E mutation and preservation of CDKN2A deletion in a novel orthotopic xenograft mouse model of progressive pleomorphic xanthoastrocytoma.
Kogiso M, Qi L, Lindsay H, Huang Y, Zhao X, Liu Z, Braun FK, Du Y, Zhang H, Bae G, Zhao S, Injac SG, Sobieski M, Brunell D, Mehta V, Tran D, Murray J, Baxter PA, Yuan XJ, Su JM, Adesina A, Perlaky L, Chintagumpala M, Parsons DW, Lau CC, Stephan CC, Lu X, Li XN. Kogiso M, et al. Among authors: huang y. Oncotarget. 2017 Sep 8;8(50):87455-87471. doi: 10.18632/oncotarget.20713. eCollection 2017 Oct 20. Oncotarget. 2017. PMID: 29152094 Free PMC article.
Impact of SCID mouse gender on tumorigenicity, xenograft growth and drug-response in a large panel of orthotopic PDX models of pediatric brain tumors.
Qi L, Kogiso M, Du Y, Zhang H, Braun FK, Huang Y, Teo WY, Lindsay H, Zhao S, Baxter P, Zhao X, Yu L, Liu Z, Zhang X, Su JM, Adesina A, Yang J, Chintagumpala M, Perlaky L, Tsz-Kwong Man C, Lau CC, Li XN. Qi L, et al. Among authors: huang y. Cancer Lett. 2020 Nov 28;493:197-206. doi: 10.1016/j.canlet.2020.08.035. Epub 2020 Sep 3. Cancer Lett. 2020. PMID: 32891713 Free PMC article.
Corrigendum to "Impact of SCID mouse gender on tumorigenicity, xenograft growth and drug-response in a large panel of orthotopic PDX models of pediatric brain tumors" [Cancer Lett. 493 (2020) 197-206].
Qi L, Kogiso M, Du Y, Zhang H, Braun FK, Huang Y, Teo WY, Lindsay H, Zhao S, Baxter P, Zhao X, Yu L, Liu Z, Zhang X, Su J, Adesina A, Yang J, Chintagumpala M, Perlaky L, Tsz-Kwong Man C, Lau CC, Li XN. Qi L, et al. Among authors: huang y. Cancer Lett. 2021 Mar 1;500:294. doi: 10.1016/j.canlet.2020.12.007. Epub 2020 Dec 23. Cancer Lett. 2021. PMID: 33358190 Free PMC article. No abstract available.
Spatial Dissection of Invasive Front from Tumor Mass Enables Discovery of Novel microRNA Drivers of Glioblastoma Invasion.
Huang Y, Qi L, Kogiso M, Du Y, Braun FK, Zhang H, Huang LF, Xiao S, Teo WY, Lindsay H, Zhao S, Baxter P, Su JMF, Adesina A, Yang J, Brabetz S, Kool M, Pfister SM, Chintagumpala M, Perlaky L, Wang Z, Zhou Y, Man TK, Li XN. Huang Y, et al. Among authors: huang lf. Adv Sci (Weinh). 2021 Dec;8(23):e2101923. doi: 10.1002/advs.202101923. Epub 2021 Nov 1. Adv Sci (Weinh). 2021. PMID: 34719887 Free PMC article.
Synergistic anti-tumor efficacy of mutant isocitrate dehydrogenase 1 inhibitor SYC-435 with standard therapy in patient-derived xenograft mouse models of glioma.
Kogiso M, Qi L, Du Y, Braun FK, Zhang H, Huang LF, Guo L, Huang Y, Teo WY, Lindsay H, Zhao S, Injac SG, Liu Z, Mehta V, Tran D, Li F, Baxter PA, Su JM, Perlaky L, Parsons DW, Chintagumpala M, Adesina A, Song Y, Li XN. Kogiso M, et al. Among authors: huang lf, huang y. Transl Oncol. 2022 Apr;18:101368. doi: 10.1016/j.tranon.2022.101368. Epub 2022 Feb 16. Transl Oncol. 2022. PMID: 35182954 Free PMC article.
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